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1.发明授权Neuropeptide El optionally combined with ACTH (7-38) for use in anti-angiogenic therapy 有权神经肽E1和在抗血管生成治疗中使用可选的ACTH（7-38）
公开(公告)号：EP2187901B1
公开(公告)日：2012-08-08
申请号：EP08802082.1
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/10 , A61K38/35 , A61P35/00 , A61P25/00 , A61P17/00 , A61P3/00 , A61P3/02 , A61P17/06 , A61P27/00 , A61P11/00 , A61P1/00 , A61P15/00 , A61P19/00 , A61P43/00
CPC分类号： A61K38/35 , A61K38/10 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2207560A2
公开(公告)日：2010-07-21
申请号：EP08802380.9
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
CPC分类号： A61K38/35 , A61K38/10 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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3.发明公开USE OF MELANOTROPIN-POTENTIATING FACTOR AS A THERAPEUTIC AGENT 审中-公开使用一个黑素-POTENZIERUNGSFAKTORS乙肝病毒感染的治疗
公开(公告)号：EP2205262A2
公开(公告)日：2010-07-14
申请号：EP08840110.4
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/07 , A61P31/18 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00
CPC分类号： A61K38/07 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Lys-Lys-GIy-Glu-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Lys-Lys-Gly-Glu-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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4.发明公开USE OF ADRENOMEDULLIN AS A THERAPEUTIC AGENT FOR THE TREATMENT OF EXCESSIVE ANGIOGENESIS 审中-公开肾上腺髓质素作为治疗剂用于治疗过度血管
公开(公告)号：EP2197467A2
公开(公告)日：2010-06-23
申请号：EP08802267.8
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/12 , A61P31/22 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00 , A61K38/22
CPC分类号： A61K38/2242 , A23L33/18 , A23L33/40 , A23V2002/00 , A61K38/2235 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , A61K2300/00 , A23V2200/308 , A23V2200/318 , A23V2200/322 , A23V2200/324 , A23V2200/326 , A23V2250/55
摘要： The present invention is directed to the use of the peptide compound His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2195012A2
公开(公告)日：2010-06-16
申请号：EP08802242.1
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/17 , A61K38/33 , A61P35/00 , A61P37/00 , A61P25/28 , A61P31/00 , A61P11/00 , A61P9/00 , A61P3/00
CPC分类号： A61K38/23 , Y02A50/385 , Y02A50/387 , Y02A50/393 , Y02A50/397 , Y02A50/402 , Y02A50/406 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423 , Y02A50/469
摘要： The present invention is directed to the use of the peptide compound Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
摘要翻译： 本发明涉及肽化合物Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro- Val-Lys-Arg-Arg-Ala-OH作为预防和/或治疗癌症，自身免疫疾病，纤维化疾病，炎性疾病，神经变性疾病，感染性疾病，肺病，心脏和血管疾病以及代谢疾病的治疗剂 。 此外，本发明涉及优选以冻干物或液体缓冲溶液或人造母乳制剂或母乳代用品形式的药物组合物，其含有肽Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu- Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH任选与至少一种药学上可接受的载体，冷冻保护剂，冻干保护剂，赋形剂和/或稀释剂一起。
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公开(公告)号：EP2190535A2
公开(公告)日：2010-06-02
申请号：EP08802602.6
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
CPC分类号： A61K38/12 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423 , A61K2300/00
摘要： The present invention is directed to the use of the peptide compound Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2190457A1
公开(公告)日：2010-06-02
申请号：EP08830174.2
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/17 , A61K38/44 , A61P35/00 , A61P31/00 , A61P37/00 , A61P9/00 , A61P25/00 , A61P3/00 , A61P11/00
CPC分类号： A61K38/1729 , Y02A50/385 , Y02A50/387 , Y02A50/393 , Y02A50/397 , Y02A50/402 , Y02A50/406 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , Y02A50/469
摘要： The present invention is directed to the use of the peptide compound Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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8.发明公开USE OF STRESSCOPIN-RELATED PEPTIDE AS A THERAPEUTIC AGENT 有权他 - 脯氨酸 - 甘氨酸 - 丝氨酸 - 精氨酸-LLE-VAL-LEU-SER-LEU-ASP-VAL-临LLE - 甘氨酸 - 亮氨酸，亮氨酸，谷氨酰胺，异亮氨酸，亮氨酸，亮氨酸，谷氨酸，谷氨酰胺-ALA-Arg- ALA-Arg-Ala-ALA-精氨酸，谷氨酸，谷氨酰胺-ALA-THR-THR-ASN-ALA-精氨酸 - 异亮氨酸，亮氨酸，丙氨酸，精氨酸-VAL-NH2在抗血管生成疗法
公开(公告)号：EP2190447A2
公开(公告)日：2010-06-02
申请号：EP08802324.7
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
CPC分类号： A61K38/22 , A23L33/18 , A23L33/40 , A23V2002/00 , A61K38/26 , Y02A50/385 , Y02A50/387 , Y02A50/393 , Y02A50/397 , Y02A50/401 , Y02A50/402 , Y02A50/406 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423 , Y02A50/465 , Y02A50/469 , Y02A50/471 , Y02A50/473 , A61K2300/00 , A23V2200/308 , A23V2200/318 , A23V2200/322 , A23V2200/324 , A23V2200/326 , A23V2250/55
摘要： The present invention is directed to the use of the peptide compound His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2188016A2
公开(公告)日：2010-05-26
申请号：EP08802149.8
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00 , A61P31/06 , A61K38/31
CPC分类号： A61K38/043 , A61K38/12 , A61K38/34 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423 , A61K2300/00
摘要： The present invention is directed to the use of the peptide compound H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2187953A2
公开(公告)日：2010-05-26
申请号：EP08830195.7
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/33 , A61P35/00 , A61P37/00 , A61P25/28 , A61P31/00 , A61P11/00 , A61P9/00 , A61P3/00 , A61K38/09
CPC分类号： A61K38/12 , A23L33/18 , A23L33/40 , A23V2002/00 , A61K38/22 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , A61K2300/00 , A23V2200/308 , A23V2200/318 , A23V2200/322 , A23V2200/324 , A23V2200/326 , A23V2250/55
摘要： The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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