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公开(公告)号：EP2274053A2
公开(公告)日：2011-01-19
申请号：EP08802520.0
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00 , A61P31/20 , A61K38/22
CPC分类号： A61K38/09 , A61K38/33 , Y02A50/385 , Y02A50/387 , Y02A50/401 , Y02A50/402 , Y02A50/406 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423 , Y02A50/465 , Y02A50/469 , Y02A50/471 , Y02A50/481 , A61K2300/00
摘要： The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-NHEt as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-NHEt optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2200629A1
公开(公告)日：2010-06-30
申请号：EP08802586.1
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
CPC分类号： C07K7/06 , A61K38/00 , C07K14/503 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Tyr-Val-Lys-Arg-Val-Lys-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Tyr-Val-Lys-Arg-Val-Lys-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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3.发明公开USE OF BFGF 1-24 AND OPTIONALLY (ARG 8) VASOPRESSIN TO TREAT EG S. PNEUMONIAE INFECTION 审中-公开bFGF的1-24和可选（ARG 8）加压素的感染HBV的OR肺炎链球菌治疗中的用途
公开(公告)号：EP2197480A2
公开(公告)日：2010-06-23
申请号：EP08785859.3
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/55 , A61K38/18 , A61K38/11 , A61P31/06 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00
CPC分类号： A61K38/12 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423 , A61K2300/00
摘要： The present invention is directed to the use of the peptide compound Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pro-Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys-Asp-Pro-Lys-Arg-Leu-Tyr optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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4.发明公开USE OF BAND 3 PROTEIN AND PACAP-27 AS A THERAPEUTIC AGENT 审中-公开他-PRO-LEU-GLN - 赖氨酸 - 苏氨酸，酪氨酸-OH和他 - 丝氨酸 - 天冬氨酸 - 甘氨酸 - 异亮氨酸，苯丙氨酸，苏氨酸，天冬氨酸，丝氨酸，酪氨酸 - 丝氨酸 - 精氨酸 - 酪氨酸 - 精氨酸 - 赖氨酸 - 谷氨酰胺-MET- 丙氨酸 - 缬氨酸 - 赖氨酸 - 赖氨酸 - 酪氨酸 - 亮氨酸酰-Ala-Ala-VAL-LEU-NH 2在HBV感染的预防和/或治疗用途
公开(公告)号：EP2197472A2
公开(公告)日：2010-06-23
申请号：EP08802577.0
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/17 , A61K38/22 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00 , A61P31/20
CPC分类号： A61K38/08 , A23C9/1526 , A23L33/18 , A23L33/40 , A61K38/2278 , A61K2300/00
摘要： The present invention is directed to the use of the combination of the His-Pro-Leu-Gln-Lys-Thr-Tyr-OH and His-Ser-Asp-Gly-lle-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2 as a therapeutic combination for prophylaxis and/or treatment of cancer, a heart and vascular disease, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, or an autoimmune disease.
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5.发明公开USE OF BUBUC AND OPTIONALLY EAA-MART1 (26-35) AS A THERAPEUTIC AGENT FOR THE TREATMENT OF HCMV INFECTIONS 审中-公开作为治疗剂BUBUC和可选EAA MART1（26-35）用于治疗HBV或巨细胞病毒感染中的用途
公开(公告)号：EP2197470A2
公开(公告)日：2010-06-23
申请号：EP08802238.9
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/17 , A61K38/33 , A61P31/22 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00
CPC分类号： C07K7/06 , A61K38/00 , C07K14/503 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Tyr-Val-Lys-Arg-Val-Lys-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Tyr-Val-Lys-Arg-Val-Lys-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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6.发明公开USE OF ANGIOTENSIN II AS A THERAPEUTIC AGENT IN THE TREATMENT OF EG S. PNEUMONIAE INFECTION 审中-公开血管紧张素II的作为治疗剂以与实施例感染的治疗用途 肺炎链球菌
公开(公告)号：EP2197465A2
公开(公告)日：2010-06-23
申请号：EP08785857.7
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/08 , A61P31/06 , A61P31/18 , A61P9/00 , A61P11/00 , A61P3/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00 , A61P31/20
CPC分类号： A61K38/085 , A61K38/35 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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7.发明公开USE OF TRP6-TRIPTORELIN AND D-LEU6-LEUPROLIDE AS THERAPEUTIC AGENTS 审中-公开USE色氨酸6-曲普瑞林和D-6亮氨酸亮丙瑞林AS的治疗剂的
公开(公告)号：EP2190453A2
公开(公告)日：2010-06-02
申请号：EP08801995.5
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
CPC分类号： A61K38/35 , A61K38/10 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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8.发明公开USE OF GLUCAGON (1-29) ALONE OR IN COMBINATION WITH NEUROPEPTIDE W30 AS A THERAPEUTIC AGENT 审中-公开使用胰高血糖素（1-29）单独或与NEURO肽W30 AS的治疗剂组合
公开(公告)号：EP2188017A2
公开(公告)日：2010-05-26
申请号：EP08802212.4
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
CPC分类号： A61K38/17 , A61K38/08 , A61K38/26 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , A61K2300/00
摘要： The present invention is directed to the use of the peptide compound Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH or its combination with the peptide Thr-Thr-Ser-Gln-Val-Arg-Pro-Arg-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2187956A2
公开(公告)日：2010-05-26
申请号：EP08802206.6
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/39 , A61K38/55 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00
CPC分类号： A61K38/11 , Y02A50/385 , Y02A50/402 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/422 , Y02A50/423
摘要： The present invention is directed to the use of the peptide compound Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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公开(公告)号：EP2187946A1
公开(公告)日：2010-05-26
申请号：EP08874950.2
申请日：2008-09-09
发明人： BEVEC, Dorian , CAVALLI, Fabio , CAVALLI, Vera , BACHER, Gerald
IPC分类号： A61K38/22 , A61P31/06 , A61P31/20 , A61P3/00 , A61P9/00 , A61P11/00 , A61P25/28 , A61P31/00 , A61P35/00 , A61P37/00
CPC分类号： A61K38/046 , A61K38/00 , C07K14/575 , Y02A50/387 , Y02A50/401 , Y02A50/402 , Y02A50/406 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , Y02A50/471 , Y02A50/481
摘要： The present invention is directed to the use of the peptide compound Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
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