发明授权
EP2231655B1 4(-3-(-2-(PHENYL)MORPHOLINO)-2-OXOPYRROLIDIN-1-YL)-N-(THIAZOL-2-YL)BENZENESULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN
有权
4-（3-（2-（苯基）吗啉代）-2-氧代吡咯烷-1-基）-N-（噻唑-2-基）苯磺酰胺和相关化合物作为离子通道调节剂来治疗疼痛
- 专利标题： 4(-3-(-2-(PHENYL)MORPHOLINO)-2-OXOPYRROLIDIN-1-YL)-N-(THIAZOL-2-YL)BENZENESULFONAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN
- 专利标题（中）： 4-（3-（2-（苯基）吗啉代）-2-氧代吡咯烷-1-基）-N-（噻唑-2-基）苯磺酰胺和相关化合物作为离子通道调节剂来治疗疼痛
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申请号： EP08850039.2申请日： 2008-11-12
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公开(公告)号： EP2231655B1公开(公告)日： 2011-08-31
- 发明人: STAMOS, Dean , MARTINBOROUGH, Esther , NEUBERT, Timothy , NUMA, Mehdi, Michel Djamel , WHITNEY, Tara , ZIMMERMANN, Nicole , KAWATKAR, Aarti, Sameer
- 申请人： Vertex Pharmaceuticals Incorporated
- 申请人地址： 130 Waverly Street Cambridge, MA 02139 US
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： 130 Waverly Street Cambridge, MA 02139 US
- 代理机构： Cohausz & Florack
- 优先权： US987485P 20071113; US88141 20080812
- 国际公布： WO2009064747 20090522
- 主分类号： C07D417/14
- IPC分类号： C07D417/14 ; A61K31/427 ; A61P25/04
摘要：
The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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