发明公开
EP2253621A1 A SET OF GELDANAMYCIN DERIVATIVES AND THEIR PREPARATION METHODS
审中-公开
VERFAHREN ZU IHRER HERSTELLUNG的EINE GRUPPE VON GELDANAMYCINDERIVATEN
- 专利标题: A SET OF GELDANAMYCIN DERIVATIVES AND THEIR PREPARATION METHODS
- 专利标题(中): VERFAHREN ZU IHRER HERSTELLUNG的EINE GRUPPE VON GELDANAMYCINDERIVATEN
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申请号: EP09703551.3申请日: 2009-01-19
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公开(公告)号: EP2253621A1公开(公告)日: 2010-11-24
- 发明人: LI, Zhuorong , PENG, Zonggen , LI, Yanping , ZHU, Jianhua , TAO, Peizhen , FAN, Bo , WANG, Yuping , SHAN, Guangzhi , WANG, Shuqin , ZHANG, Tian , JIANG, Jiandong
- 申请人: Institute Of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- 申请人地址: 1 Tian Tan Xi Li Chongwen 100050 Beijing CN
- 专利权人: Institute Of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- 当前专利权人: Institute Of Medicinal Biotechnology, Chinese Academy of Medical Sciences
- 当前专利权人地址: 1 Tian Tan Xi Li Chongwen 100050 Beijing CN
- 代理机构: Samson & Partner
- 优先权: CN200810001170 20080118
- 国际公布: WO2009092295 20090730
- 主分类号: C07D225/06
- IPC分类号: C07D225/06 ; C07H19/06 ; C07D401/12 ; A61K31/395 ; A61K31/4427 ; A61P31/12 ; A61P35/00
摘要:
A set of geldanamycin derivatives and their preparation methods. Pharmaceutical compositions comprising the said compounds as an active ingredient which are used as antivirus and antitumor agents. The said derivatives are used in the manufacture of heat shock protein 90(Hsp 90) inhibiting agents which have the utility as antivirus and antitumor agents.
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