发明公开
EP2257291A2 PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS IN THE TREATMENT OF SKIN DISORDERS
审中-公开
哒嗪衍生物及其用作治疗剂的皮肤疾病的治疗
- 专利标题： PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS IN THE TREATMENT OF SKIN DISORDERS
- 专利标题（中）： 哒嗪衍生物及其用作治疗剂的皮肤疾病的治疗
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申请号： EP09713747.5申请日： 2009-02-19
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公开(公告)号： EP2257291A2公开(公告)日： 2010-12-08
- 发明人: BILLICH, Andreas , WINTHER, Michael, D. , GOLDBERG, Yigal, Paul , WINZENBURG, Gesine , RAPP, Karin , FRITZE, Andreas
- 申请人： Xenon Pharmaceuticals Inc. , Novartis AG
- 申请人地址： 3650 Gilmore Way Burnaby, BC V5G 4W8 CA
- 专利权人： Xenon Pharmaceuticals Inc.,Novartis AG
- 当前专利权人： Xenon Pharmaceuticals Inc.,Novartis AG
- 当前专利权人地址： 3650 Gilmore Way Burnaby, BC V5G 4W8 CA
- 代理机构： Giovannini, Francesca
- 优先权： US36685 20080225
- 国际公布： WO2009106991 20090903
- 主分类号： A61K31/501
- IPC分类号： A61K31/501 ; A61P17/00 ; A61P17/08 ; A61P17/10 ; A61K9/00 ; A61K47/08 ; A61K47/10 ; A61K47/32
摘要：
Methods of treating an SCD-mediated skin disorder or condition in a mammal, preferably a human, including administering to a mammal in need thereof a compound of formula (I): where x, y, W, V, R
2 , R
3 , R
4 , R
5 , R
6 , R
6a , R
7 , R
7a , R
8 , R
8a , R
9 and R
9a are defined herein, and compositions including a compound of formula (I).
2 , R
3 , R
4 , R
5 , R
6 , R
6a , R
7 , R
7a , R
8 , R
8a , R
9 and R
9a are defined herein, and compositions including a compound of formula (I).
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