发明授权
EP2297103B1 HYDROXYPHENYLSULFONAMIDES AS ANTIAPOPTOTIC BCL INHIBITORS
有权
HYDROXYPHENYLSULFONSÄUREAMIDEALS抗凋亡BCL-抑制剂
- 专利标题: HYDROXYPHENYLSULFONAMIDES AS ANTIAPOPTOTIC BCL INHIBITORS
- 专利标题(中): HYDROXYPHENYLSULFONSÄUREAMIDEALS抗凋亡BCL-抑制剂
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申请号: EP09763373.9申请日: 2009-06-08
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公开(公告)号: EP2297103B1公开(公告)日: 2012-01-04
- 发明人: KIM, Kyoung, S. , BORZILLERI, Robert, M. , CAI, Zhen-wei , YEUNG, Kap-sun
- 申请人: Bristol-Myers Squibb Company
- 申请人地址: Route 206 and Province Line Road P.O. Box 4000 Princeton NJ 08543-4000 US
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: Route 206 and Province Line Road P.O. Box 4000 Princeton NJ 08543-4000 US
- 代理机构: Reitstötter - Kinzebach
- 优先权: US59853P 20080609
- 国际公布: WO2009152082 20091217
- 主分类号: C07D213/65
- IPC分类号: C07D213/65 ; C07D213/68 ; C07D213/71 ; C07D213/81 ; C07D213/40 ; C07D277/64 ; C07D403/04 ; C07C15/04 ; A61K31/4406 ; A61P35/00
摘要:
The present invention provides compound of Formula (I): or a stereoisomer, tautomer, salt or solvate thereof, wherein the variables are defined herein. The compounds of formula (I) are inhibitors of Bcl-2 family antiapoptotic proteins, compositions containing the compounds and methods of treating diseases using the compounds.
公开/授权文献
- EP2297103A1 HYDROXYPHENYLSULFONAMIDES AS ANTIAPOPTOTIC BCL INHIBITORS 公开/授权日:2011-03-23
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