发明公开
- 专利标题: NANOMETER-SIZED PRODRUGS OF NSAIDS
- 专利标题(中): 前体药物不甾体类抗炎基金与该纳米范围内的尺寸
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申请号: EP09758861.0申请日: 2009-04-08
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公开(公告)号: EP2300451A1公开(公告)日: 2011-03-30
- 发明人: YU, John, S. , LEE, Bong, Seop
- 申请人: Cedars-Sinai Medical Center
- 申请人地址: 8700 Beverly Boulevard Los Angeles, California 90048 US
- 专利权人: Cedars-Sinai Medical Center
- 当前专利权人: Cedars-Sinai Medical Center
- 当前专利权人地址: 8700 Beverly Boulevard Los Angeles, California 90048 US
- 代理机构: Harrison Goddard Foote
- 优先权: US58189P 20080602; US58190P 20080602; PCT/US2008/088541 20081230
- 国际公布: WO2009148698 20091210
- 主分类号: C07D339/02
- IPC分类号: C07D339/02
摘要:
The present invention describes nanoprodrugs of non-steroidal anti-inflammatory drug (NSAIDs) and nanoprodrugs of α-lipoic acid-containing and NSAIDs. These nanoprodrugs have antioxidant properties and stimuli-responsiveness, which can be used to treat various disease conditions.
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