- 专利标题: GENE THERAPY VECTORS AND CYTOSINE DEAMINASES
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申请号: EP09820986.9申请日: 2009-09-26
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公开(公告)号: EP2346995B1公开(公告)日: 2018-11-07
- 发明人: GRUBER, Harry, E. , JOLLY, Douglas , PEREZ, Omar , LOGG, Christopher R.
- 申请人: Tocagen Inc.
- 申请人地址: 3030 Bunker Hill Street Suite 230 San Diego, CA 92109 US
- 专利权人: Tocagen Inc.
- 当前专利权人: Tocagen Inc.
- 当前专利权人地址: 3030 Bunker Hill Street Suite 230 San Diego, CA 92109 US
- 代理机构: Daniels, Jeffrey Nicholas
- 优先权: US186823P 20090613; US100666P 20080926; US120618P 20081208
- 国际公布: WO2010045002 20100422
- 主分类号: C12N15/52
- IPC分类号: C12N15/52 ; C12N5/10 ; C12N15/867 ; C07K14/39 ; C12N9/10 ; C07K14/55 ; C07K14/57 ; C12N9/78
摘要:
This disclosure provides modified cytosine deaminases (CDs). The disclosure further relates to cells and vector expressing or comprising such modified CDs and methods of using such modified CDs in the treatment of disease and disorders.
公开/授权文献
- EP2346995A2 GENE THERAPY VECTORS AND CYTOSINE DEAMINASES 公开/授权日:2011-07-27
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