发明公开
EP2392923A1 Method of prodcucing proteins comprising unnatural amino acid
有权
Methode zur Herstellung von Proteinen mitunnatürlichenAminosäuren
- 专利标题： Method of prodcucing proteins comprising unnatural amino acid
- 专利标题（中）： Methode zur Herstellung von Proteinen mitunnatürlichenAminosäuren
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申请号： EP11165139.4申请日： 2004-04-16
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公开(公告)号： EP2392923A1公开(公告)日： 2011-12-07
- 发明人: Deiters, Alexander , Cropp, Ashton T. , Chin, Jason W. , Anderson, Christopher J. , Schultz, Peter G.
- 申请人： The Scripps Research Institute
- 申请人地址： Office of Patent Counsel 10550 North Torrey Pines Road Mail TPC-8 La Jolla, CA 92037 US
- 专利权人： The Scripps Research Institute
- 当前专利权人： The Scripps Research Institute
- 当前专利权人地址： Office of Patent Counsel 10550 North Torrey Pines Road Mail TPC-8 La Jolla, CA 92037 US
- 代理机构： Casley, Christopher Stuart
- 优先权： US479931P 20030618; US493014P 20030805; US496548P 20030819
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K38/17 ; C12N5/00 ; C12N9/00 ; C12N15/85
摘要：
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNAsynthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
公开/授权文献
- EP2392923B1 Method of producing proteins comprising unnatural amino acid 公开/授权日：2014-05-21
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