发明公开
EP2401273A1 TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS
审中-公开
TRICYCLISCHE PYRAZOLOPYRIDINE ALS KINASEINHIBITOREN
- 专利标题: TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS
- 专利标题(中): TRICYCLISCHE PYRAZOLOPYRIDINE ALS KINASEINHIBITOREN
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申请号: EP10706860.3申请日: 2010-02-25
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公开(公告)号: EP2401273A1公开(公告)日: 2012-01-04
- 发明人: ARONOV, Alex , COME, Jon , COTTRELL, Kevin , GREY, Ronald , LE TIRAN, Amaud , MARONE, Valerie , MARTINEZ-BOTELLA, Gabriel , MESSERSMITH, David , HUCK, Emilie, Porter
- 申请人: Vertex Pharmaceuticals Incorporated
- 申请人地址: 130 Waverly Street Cambridge, MA 02139 US
- 专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人地址: 130 Waverly Street Cambridge, MA 02139 US
- 代理机构: Coles, Andrea Birgit
- 优先权: US156139P 20090227
- 国际公布: WO2010135014 20101125
- 主分类号: C07D417/04
- IPC分类号: C07D417/04 ; C07D513/04 ; C07D417/14 ; A61K31/4965 ; A61K31/4427 ; A61K31/506 ; A61K31/501 ; A61P29/00 ; A61P37/00
摘要:
The present invention relates to compounds useful as inhibitors of P13K, particularly of P13Kgamma. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of several diseases, such as cancer and autoimmune diseases.
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