发明公开
- 专利标题: METHOD FOR PRODUCING ISOTHIAZOLE DERIVATIVE
- 专利标题(中): 生产异噻唑衍生物的方法
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申请号: EP10769860.7申请日: 2010-04-30
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公开(公告)号: EP2426114A1公开(公告)日: 2012-03-07
- 发明人: NAKAMURA, Takayuki , KUMAGAI, Hironobu , OGAWA, Mahito
- 申请人: Ihara Chemical Industry Co., Ltd.
- 申请人地址: 4-26 Ikenohata 1-chome Taito-ku Tokyo 110-0008 JP
- 专利权人: Ihara Chemical Industry Co., Ltd.
- 当前专利权人: Ihara Chemical Industry Co., Ltd.
- 当前专利权人地址: 4-26 Ikenohata 1-chome Taito-ku Tokyo 110-0008 JP
- 代理机构: Bates, Philip Ian
- 优先权: JP2009111840 20090501; JP2009111841 20090501
- 国际公布: WO2010126170 20101104
- 主分类号: C07D275/02
- IPC分类号: C07D275/02
摘要:
A process for producing 3,4-dichloro-5-cyanoisothiazole represented by a general formula (3):
the process comprising:
reacting a nitrile compound represented by a general formula (1):
(wherein "n" denotes an integer of 0 to 2), with sulfur chloride represented by a general formula (2):
[Chemical Formula 18] S m Cl 2 (2)
(wherein "m" represents an integer of 1 to 2), or a mixture thereof in an aprotic polar solvent. There is provided a process for producing 3,4-dichloro-5-cyanoisothiazole, which is capable of suppressing by-production of a waste, without using a raw material having a having a strong toxicity; and is capable of providing a product having a higher purity in a high yield and efficiency in an industrial scale, in a simple manner.
the process comprising:
reacting a nitrile compound represented by a general formula (1):
(wherein "n" denotes an integer of 0 to 2), with sulfur chloride represented by a general formula (2):
[Chemical Formula 18] S m Cl 2 (2)
(wherein "m" represents an integer of 1 to 2), or a mixture thereof in an aprotic polar solvent. There is provided a process for producing 3,4-dichloro-5-cyanoisothiazole, which is capable of suppressing by-production of a waste, without using a raw material having a having a strong toxicity; and is capable of providing a product having a higher purity in a high yield and efficiency in an industrial scale, in a simple manner.
公开/授权文献
- EP2426114B1 METHOD FOR PRODUCING ISOTHIAZOLE DERIVATIVE 公开/授权日:2013-11-20
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