发明授权
- 专利标题： BIOMARKERS FOR DETERMINING SENSITIVITY OF BREAST CANCER CELLS TO HER2-TARGETED THERAPY
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申请号： EP10720095.8申请日： 2010-05-13
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公开(公告)号： EP2430443B1公开(公告)日： 2018-06-27
- 发明人: KIM, Phillip , LIU, Xinjun , KIRKLAND, Richard , LEE, Tani , YBARRONDO, Belen , SINGH, Sharat
- 申请人： Pierian Holdings, Inc.
- 申请人地址： 405 Duke Drive, Suite 240 Franklin, TN 37067 US
- 专利权人： Pierian Holdings, Inc.
- 当前专利权人： Pierian Holdings, Inc.
- 当前专利权人地址： 405 Duke Drive, Suite 240 Franklin, TN 37067 US
- 代理机构： J A Kemp
- 优先权： US178458P 20090514; US180787P 20090522; US187246P 20090615; US228522P 20090724; US235646P 20090820; US241804P 20090911; US262856P 20091119; US265227P 20091130
- 国际公布： WO2010132723 20101118
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; G01N33/532 ; G01N33/533 ; G01N33/535 ; G01N33/543 ; G01N33/574
摘要：
The present invention provides compositions and methods for detecting the expression and/or activation states of components of signal transduction pathways in cells such as tumor cells. Information on the expression and/or activation states of components of signal transduction pathways derived from use of the present invention can be used for cancer diagnosis, prognosis, and in the design of cancer treatments.
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