发明公开
- 专利标题： UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME
- 专利标题（中）： Xa因子抑制剂的解毒剂的单配方中预防出血
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申请号： EP10737699.8申请日： 2010-07-14
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公开(公告)号： EP2453910A1公开(公告)日： 2012-05-23
- 发明人: SINHA, Uma , LU, Genmin , HUTCHALEELAHA, Athiwat , HOLLENBACH, Stanley J.
- 申请人： Portola Pharmaceuticals, Inc.
- 申请人地址： 270 East Grand Avenue Suite 22 South San Francisco California 94080 US
- 专利权人： Portola Pharmaceuticals, Inc.
- 当前专利权人： Portola Pharmaceuticals, Inc.
- 当前专利权人地址： 270 East Grand Avenue Suite 22 South San Francisco California 94080 US
- 代理机构： Sexton, Jane Helen
- 优先权： US225887P 20090715
- 国际公布： WO2011008885 20110120
- 主分类号： A61K38/48
- IPC分类号： A61K38/48 ; C12N9/64 ; A61P7/00 ; A61P7/04
摘要：
The present invention relates unit dose formulations of antidotes to anticoagulants targeting factor Xa. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor.
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