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1.发明授权UNIT DOSE FORMULATION OF ANTIDOTE FOR FACTOR XA INHIBITORS FOR USE IN PREVENTING BLEEDING 有权EINZELDOSISFORMULIERUNG VON ANTIDOTENFÜRFAKTOR-XA-HEMMER ZUR PRURVENTION VON BLUTUNG
公开(公告)号：EP2453910B1
公开(公告)日：2016-08-31
申请号：EP10737699.8
申请日：2010-07-14
CPC分类号： A61K38/4846 , A61K9/0019 , C12N9/6432 , C12Y304/21006
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2.发明公开INTRAVENOUS AND ORAL DOSING OF A DIRECT-ACTING AND REVERSIBLE P2Y12 INHIBITOR 审中-公开一个直接作用的和可逆的P2Y12抑制剂的静脉内和口服剂量
公开(公告)号：EP2079464A2
公开(公告)日：2009-07-22
申请号：EP08747561.2
申请日：2008-05-02
发明人： GRETLER, Daniel, D. , CONLEY, Pamela, B. , ANDRE, Patrick , HUTCHALEELAHA, Athiwat , PHILLIPS, David, R. , PANDEY, Anjali , WOLIN, Huang , SCARBOROUGH, Robert, M.
IPC分类号： A61K31/216 , A61K31/517 , A61P7/02
CPC分类号： A61K31/517 , A61K31/216 , A61K2300/00
摘要： The invention provides methods and compositions for rapid and reversible inhibition of platelet aggregation in human subjects in need thereof by administering compounds of the formula: (I) alone or in combination with a second agent which can be aspirin or a thrombolytic agent.
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3.发明公开UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME 有权Xa因子抑制剂的解毒剂的单配方中预防出血
公开(公告)号：EP2453910A1
公开(公告)日：2012-05-23
申请号：EP10737699.8
申请日：2010-07-14
CPC分类号： A61K38/4846 , A61K9/0019 , C12N9/6432 , C12Y304/21006
摘要： The present invention relates unit dose formulations of antidotes to anticoagulants targeting factor Xa. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor.
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