发明公开
- 专利标题: 3-PHENOXYMETHYLPYRROLIDINE COMPOUNDS
- 专利标题(中): 3-苯氧基甲基吡咯烷化合物
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申请号: EP10735120.7申请日: 2010-07-14
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公开(公告)号: EP2456436A1公开(公告)日: 2012-05-30
- 发明人: STANGELAND, Eric L. , SCHMIDT, Jane , SAITO, Daisuke Roland , HUGHES, Adam , PATTERSON, Lori Jean
- 申请人: Theravance, Inc.
- 申请人地址: 901 Gateway Boulevard South San Francisco, CA 94080 US
- 专利权人: Theravance, Inc.
- 当前专利权人: Theravance, Inc.
- 当前专利权人地址: 901 Gateway Boulevard South San Francisco, CA 94080 US
- 代理机构: Scott, Susan Margaret
- 优先权: US227207P 20090721
- 国际公布: WO2011011231 20110127
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61P29/00
摘要:
In one aspect, the invention relates to compounds of formula (I) where R
1-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
1-6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. The compounds of formula I are serotonin and norepinephrine reuptake inhibitors. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
公开/授权文献
- EP2456436B1 3-PHENOXYMETHYLPYRROLIDINE COMPOUNDS 公开/授权日:2014-06-25
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