发明公开
- 专利标题: FULLY HUMAN ANTIBODIES TO BTLA
- 专利标题(中): 全人抗体BTLA
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申请号: EP10737222.9申请日: 2010-07-26
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公开(公告)号: EP2459594A1公开(公告)日: 2012-06-06
- 发明人: MATARAZA, Jennifer, Marie , VAN ELSAS, Andrea , KORMAN, Alan, J. , HALK, Edward, L. , THUDIUM, Kent, B. , SELBY, Mark , SPROUL, Timothy, W. , LEBLANC, Heidi, N.
- 申请人: N.V. Organon , Medarex, Inc.
- 申请人地址: Kloosterstraat 6 5349 AB Oss NL
- 专利权人: N.V. Organon,Medarex, Inc.
- 当前专利权人: N.V. Organon,Medarex, Inc.
- 当前专利权人地址: Kloosterstraat 6 5349 AB Oss NL
- 代理机构: Reitstötter - Kinzebach
- 优先权: US230332P 20090731; US257612P 20091103
- 国际公布: WO2011014438 20110203
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K39/395 ; A61P37/06
摘要:
The present invention relates to binding compounds specific for BTLA and uses thereof. More specifically, the invention relates to fully human antibodies that recognize human BTLA and modulate its activity in cancer, inflammatory, and autoimmune disorders.
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