发明授权
- 专利标题： LIPOSOME NANOPARTICLES FOR TUMOUR MAGNETIC RESONANCE IMAGING
- 专利标题（中）： 纳米脂质体肿瘤的磁成像
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申请号： EP10781995.5申请日： 2010-11-19
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公开(公告)号： EP2501415B1公开(公告)日： 2015-03-18
- 发明人: KAMALY, Nazila , KALBER, Tammy, Louise , KENNY, Gavin, David , THANOU, Maya , MILLER, Andrew, David , BELL, Jimmy
- 申请人： Medical Research Council , Imperial Innovations Limited
- 申请人地址： 2nd Floor David Phillips Building Polaris House North Star Avenue Swindon Wiltshire SN2 1FL GB
- 专利权人： Medical Research Council,Imperial Innovations Limited
- 当前专利权人： Medical Research Council,Imperial Innovations Limited
- 当前专利权人地址： 2nd Floor David Phillips Building Polaris House North Star Avenue Swindon Wiltshire SN2 1FL GB
- 代理机构： Andrews, Timothy Stephen
- 优先权： GB0920304 20091120
- 国际公布： WO2011061541 20110526
- 主分类号： A61K49/18
- IPC分类号： A61K49/18 ; B82Y15/00
摘要：
The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium(III)2-{4,7-bis-carboxymethyl-10-[(N,N-distearylamidomethyl-N'-amido-methyl]-1,4,7,10-tetra-azacyclododec-1-yl}-acetic acid), characterised in that said liposome further comprises a neutral, fully saturated phospholipid component (e.g. DSPC (1,2-distearoyl-sn-glycero-3-phosphocholine]), which are of particular use in the preparation of magnetic resonance contrast agents for enhancing a magnetic resonance image of tumours in a mammal.
公开/授权文献
- EP2501415A1 LIPOSOME NANOPARTICLES FOR TUMOR MAGNETIC RESONANCE IMAGING 公开/授权日：2012-09-26
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