发明公开
- 专利标题： Pharmaceutical compositions of rhein or diacerein
- 专利标题（中）： 药物化学药物
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申请号： EP12178127.2申请日： 2008-09-16
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公开(公告)号： EP2520286A1公开(公告)日： 2012-11-07
- 发明人: Dabre, Rahul , Jain, Girish, Kumar , Sandal, Roshanlal , Thakkar, Vikrant
- 申请人： Wockhardt Limited
- 申请人地址： D-4, MIDC Industrial Area Chikalthana Aurangabad 431210 IN
- 专利权人： Wockhardt Limited
- 当前专利权人： Wockhardt Limited
- 当前专利权人地址： D-4, MIDC Industrial Area Chikalthana Aurangabad 431210 IN
- 代理机构： May, Mark Andrew
- 优先权： INMU18992007 20070927; INMU18982007 20070927; INMU19002007 20070927; INMU19012007 20070927; INMU05772008 20080324; INMU05782008 20080324; INMU05792008 20080324; INMU05802008 20080324; INMU11142008 20080526; INMU15192008 20080718; INMU15202008 20080718
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K9/16 ; A61K9/48 ; A61K9/58 ; A61P19/02 ; A61K31/192 ; A61P29/00
摘要：
The invention relates to pharmaceutical compositions of rhein or diacerein, or salts or esters or prodrugs thereof which are bioequivalent to a 50 mg diacerein formulation marketed under the trade name Art 50 ® . The compositions exhibit no variability in fed and fasted state conditions. The compositions also result in significant reduction in side effects such as, soft stools as compared to Art 50 ® . The invention also relates to the methods for preparing such compositions.
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