发明公开
EP2539365A2 METHOD OF INDUCING THE PRODUCTION OF PROTECTIVE ANTI-HIV-1 ANTIBODIES
审中-公开
方法对于确保保护性抗体对HIV-1的生产
- 专利标题： METHOD OF INDUCING THE PRODUCTION OF PROTECTIVE ANTI-HIV-1 ANTIBODIES
- 专利标题（中）： 方法对于确保保护性抗体对HIV-1的生产
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申请号： EP11747821.4申请日： 2011-02-25
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公开(公告)号： EP2539365A2公开(公告)日： 2013-01-02
- 发明人: HAYNES, Barton, F. , LIAO, Hua-Xin , TOMARAS, Georgia , KEPLER, Thomas, B. , HWANG, Kwan-Ki , ALAM, S., Munir , LIU, Yang , HOLL, T., Matt , YANG, Guang , KELSOE, Garnett , BONSIGNORI, Mattia
- 申请人： Duke University
- 申请人地址： P.O. Box 90083 Durham, NC 27708-0083 US
- 专利权人： Duke University
- 当前专利权人： Duke University
- 当前专利权人地址： P.O. Box 90083 Durham, NC 27708-0083 US
- 代理机构： Atkinson, Peter Birch
- 优先权： US282526P 20100225; US344457P 20100727; US344580P 20100825; US344622P 20100901
- 国际公布： WO2011106100 20110901
- 主分类号： C07K16/10
- IPC分类号： C07K16/10 ; C12N15/13 ; A61K39/42 ; A61P31/18
摘要：
The present invention relates, in general, to an immunogen for HIV vaccination and, in particular, to a method of inducing the production of protective anti-HIV antibodies by targeting B cell germline and clone intermediates using a combination of HIV envelope and non-HIV immunogens. The invention also relates to compositions suitable for use in such a method.
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