发明公开
EP2611823A4 PEPTIDE CONTAINING MULTIPLE N-LINKED GLYCOSYLATION SEQUONS
有权
PEPTID MIT MEHREREN N-GEKOPPELTEN GLYCOSYLIERUNGS-SEQONON
- 专利标题: PEPTIDE CONTAINING MULTIPLE N-LINKED GLYCOSYLATION SEQUONS
- 专利标题(中): PEPTID MIT MEHREREN N-GEKOPPELTEN GLYCOSYLIERUNGS-SEQONON
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申请号: EP11820973申请日: 2011-09-02
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公开(公告)号: EP2611823A4公开(公告)日: 2013-12-11
- 发明人: SZYMANSKI CHRISTINE , NOTHAFT HARALD
- 申请人: UNIV ALBERTA
- 专利权人: UNIV ALBERTA
- 当前专利权人: UNIV ALBERTA
- 优先权: US37989610 2010-09-03
- 主分类号: C07K14/205
- IPC分类号: C07K14/205 ; A61K39/106 ; A61K39/116 ; A61K39/385 ; A61K39/39 ; A61P31/04 ; A61P37/04 ; C07K7/06 ; C07K7/08 ; C07K9/00 ; C07K19/00 ; C12N15/00 ; C12N15/31 ; C12N15/62 ; G01N33/564
摘要:
Described herein is a peptide, referred to as a GlycoTag peptide, that includes repeats of an N-linked glycosylation sequon that is naturally present in C. jejuni. The GlycoTag peptide can be in a purified and isolated form following expression of a construct encoding the GlycoTag peptide or it is, in whole or in part, a synthetic peptide. The GlycoTag peptide is typically used with glycans attached thereto. The GlycoTag peptide can be used alone or in combination with different proteins or peptides and can be incorporated into a chimeric protein or peptide for use in the development of antigen/antibody delivery systems, the preparation of vaccines, pharmaceuticals and diagnostic tests, and research into therapies for countering Campylobacter and other infections.
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