发明公开
- 专利标题: HETEROARYLS AND USES THEREOF
- 专利标题(中): 杂种及其用途
-
申请号: EP11833402.8申请日: 2011-10-13
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公开(公告)号: EP2627181A2公开(公告)日: 2013-08-21
- 发明人: FREEZE, Brian, S. , HIROSE, Masaaki , LEE, Hong Myung , SELLS, Todd, B. , SHI, Zhan , TAKAOKA, Leo, R. , VYSKOCIL, Stepan , XU, Tianlin
- 申请人: Millennium Pharmaceuticals, Inc.
- 申请人地址: 40 Landsdowne Street Cambridge, MA 02139 US
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: 40 Landsdowne Street Cambridge, MA 02139 US
- 代理机构: Harris, Jennifer Lucy
- 优先权: US392515P 20101013
- 国际公布: WO2012051410 20120419
- 主分类号: A01N43/78
- IPC分类号: A01N43/78 ; A61K31/425 ; A01N43/16 ; A61K31/35 ; A61K31/365
摘要:
This invention provides compounds of formula I-A or I-B: wherein HY, G
1 G
2 , R
2 , R
12 , W
1 , W
2 , n, and Ring A are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
1 G
2 , R
2 , R
12 , W
1 , W
2 , n, and Ring A are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
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