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    MULTIPLEXED ASSAY
    3.
    发明公开
    MULTIPLEXED ASSAY 审中-实审

    公开(公告)号：EP4354141A3

    公开(公告)日：2024-07-10

    申请号：EP23211967.7

    申请日：2019-12-13

    申请人： Osler Diagnostics Limited

    发明人： BALDWIN, Dene ,  PSARROS, Konstantinos ,  EDINGTON, David William Neil

    IPC分类号： G01N33/543

    CPC分类号： G01N33/54353 ,  G01N33/54366

    摘要： A microfluidic device is provided for conducting multiplex immunoassays to detect multiple target analytes in a liquid sample using a set of tags and anti-tags. The device comprises an array of different anti-tags immobilised on a surface of a sensor for measuring a signal. Each anti-tag is arranged to immobilise a tagged antibody or tagged antigen thereby in use separating tagged immune complexes from the liquid phase affecting the signal measured. The device comprises a sensor chamber for tagged immune complexes to form in the liquid phase and one or more detection zones each comprising the array of different anti-tags for immobilising tagged immune complexes. In use, liquid comprising the tagged immune complexes flows or is fluidically driven from the sensor chamber to the detection zone(s).

    SCHIFF BASE OLIGOMERS
    9.
    发明公开
    SCHIFF BASE OLIGOMERS 审中-实审

    公开(公告)号：EP4303274A3

    公开(公告)日：2024-04-10

    申请号：EP23212811.6

    申请日：2021-03-05

    申请人： The Boeing Company

    发明人： ZWEIG, Andrew Michael ,  SCHUETTE, Waynie M.

    IPC分类号： C09D5/08 ,  C08G12/12 ,  C08G18/24 ,  C08G18/38 ,  C08G18/54

    摘要： Aspects of the present disclosure relate to Schiff base oligomers and uses thereof. In at least one aspect, an oligomer is represented by Formula (IV) wherein each instance of R 9 is independently selected from the group consisting of alkyl, cycloalkyl, aryl, heteroaryl, and ether. Each instance of R 28 and R 29 of Formula (IV) is independently selected from the group consisting of hydrogen, alkyl, cycloalkyl, and aryl. Each instance of R 33 of Formula (IV) is independently selected from the group consisting of alkyl, cycloalkyl, aryl, heterocyclyl, and a bond. Each instance of R 41 of Formula (IV) is independently -NH- or a bond and each instance of R 40 is independently -NH- or -NH-NH-. Each instance of R 42 of Formula (IV) is independently -NH- or a bond and each instance of R 43 is independently -NH- or -NH-NH-.