发明公开
EP2630152A1 NUCLEOTIDE ANALOGUE, METHOD OF SYNTHESIS OF NUCLEOTIDE ANALOGUE, USE OF NUCLEOTIDE ANALOGUE, ANTIVIRAL PRO-NUCLEOTIDE, PHARMACEUTICAL COMPOSITION
有权
核苷酸类似物,PROCESS用于合成的核苷酸类似物,采用了核苷酸类似物,抗病PRONUCLEOTID,药物组合物
- 专利标题: NUCLEOTIDE ANALOGUE, METHOD OF SYNTHESIS OF NUCLEOTIDE ANALOGUE, USE OF NUCLEOTIDE ANALOGUE, ANTIVIRAL PRO-NUCLEOTIDE, PHARMACEUTICAL COMPOSITION
- 专利标题(中): 核苷酸类似物,PROCESS用于合成的核苷酸类似物,采用了核苷酸类似物,抗病PRONUCLEOTID,药物组合物
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申请号: EP11781885.6申请日: 2011-10-13
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公开(公告)号: EP2630152A1公开(公告)日: 2013-08-28
- 发明人: KRASZEWSKI, Adam , ROMANOWSKA, Joanna , SOBKOWSKI, Micha , SZYMANSKA-MICHALAK, Agnieszka , STAWINSKI, Jacek , BORYSKI, Jerzy , LIPNIACKI, Andrzej , PIASEK, Andrzej
- 申请人: Instytut Chemii Bioorganicznej PAN , Narodowy Instytut Leków
- 申请人地址: ul. Z. Noskowskiego 12/14 61-704 Poznan PL
- 专利权人: Instytut Chemii Bioorganicznej PAN,Narodowy Instytut Leków
- 当前专利权人: Instytut Chemii Bioorganicznej PAN,Narodowy Instytut Leków
- 当前专利权人地址: ul. Z. Noskowskiego 12/14 61-704 Poznan PL
- 代理机构: Twardowska, Aleksandra
- 优先权: PL39270210P 20101019
- 国际公布: WO2012053917 20120426
- 主分类号: C07H19/06
- IPC分类号: C07H19/06 ; C07H19/16 ; A61P31/18
摘要:
The object of the invention are nucleotide analogues, antiviral pro-nucleotides, a use of nucleotide analogues and pharmaceutical composition, a phosphorylating agent for synthesis of nucleotide analogue, and a method of synthesis of nucleotide analogue. More precisely, the invention applies to the new group of nucleotide analogues and their use in partial or complete inhibition of human immunodeficiency virus (HIV).
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