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1.发明公开
公开(公告)号：EP3856148A2
公开(公告)日：2021-08-04
申请号：EP19865889.0
申请日：2019-09-26
发明人： WIKTORSKA, Katarzyna , MIELCZAREK, Lidia , CHILMONCZYK, Zdzis aw , SUCHOCKI, Piotr , KRUG, Pamela , MAZUR, Maciej , G OWALA, Paulina
IPC分类号： A61K9/127 , A61K31/095 , A61P35/00
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2.发明授权NUCLEOTIDE ANALOGUE, METHOD OF SYNTHESIS OF NUCLEOTIDE ANALOGUE, USE OF NUCLEOTIDE ANALOGUE, ANTIVIRAL PRO-NUCLEOTIDE, PHARMACEUTICAL COMPOSITION 有权核苷酸类似物，PROCESS用于合成的核苷酸类似物，采用了核苷酸类似物，抗病PRONUCLEOTID，药物组合物
公开(公告)号：EP2630152B1
公开(公告)日：2014-11-26
申请号：EP11781885.6
申请日：2011-10-13
发明人： KRASZEWSKI, Adam , ROMANOWSKA, Joanna , SOBKOWSKI, Micha , SZYMANSKA-MICHALAK, Agnieszka , STAWINSKI, Jacek , BORYSKI, Jerzy , LIPNIACKI, Andrzej , PIASEK, Andrzej
CPC分类号： C07F9/65616 , C07F9/65586 , C07H19/10 , C07H19/20
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3.发明公开
公开(公告)号：EP3843754A1
公开(公告)日：2021-07-07
申请号：EP19853302.8
申请日：2019-08-26
申请人： Narodowy Instytut Leków W Warszawie , Uniwersytet Warszawski , Warszawski Uniwersytet Medyczny , Instytut Medycyny Doswiadczalnej I Klinicznej Im. M. Mossakowskiego, Pan
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4.发明公开A METHOD OF EVALUATING THE THERAPEUTIC EFFICACY OF BACTERIOPHAGES 有权VERFAHREN ZUR BEWERTUNG DER THERAPEUTISCHEN WIRKSAMKEIT VON BAKTERIOPHAGEN
公开(公告)号：EP2872156A1
公开(公告)日：2015-05-20
申请号：EP13741984.2
申请日：2013-07-13
申请人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Instytut Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk , Narodowy Instytut Leków , Szkola Glówna Gospodarstwa Wiejskiego W Warszawie , Wojskowy Instytut Higieny I Epidemiologii
发明人： LOBOCKA, Malgorzata , GLOWACKA, Aleksandra , DABROWSKI, Kamil , HEJNOWICZ, Monika S. , GOZDEK, Agnieszka , WEBER-DABROWSKA, Beata , GÓRSKI, Andrzej , EMPEL, Joanna , HRYNIEWICZ, Waleria , KWIATEK, Magdalena , PARASION, Sylwia , GRYKO, Romuald
IPC分类号： A61K35/76
CPC分类号： G01N33/5085 , A61K35/76 , G01N2333/4353 , Y02A50/475 , Y02A50/481
摘要： The subject of the present invention is a novel use of a nematode in the evaluation of the therapeutic efficacy of bacteriophage preparations used in, or capable of being used in the treatment of infections caused by pathogenic bacteria in humans or animals.
摘要翻译： 本发明的主题是线虫评估用于或能够用于治疗由人或动物中的病原菌引起的感染的噬菌体制剂的治疗功效的新用途。
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5.发明公开DERIVATIVES OF CAMPTOTHECIN, A METHOD OF PRODUCING THEM AND THEIR USE 有权CAMPTOTHECIN-DERIVATE，EIN VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
公开(公告)号：EP2912039A1
公开(公告)日：2015-09-02
申请号：EP13824167.4
申请日：2013-10-25
发明人： KOZERSKI, Lech , KAWECKI, Robert , NAUMCZUK, Beata , HYZ, Karolina , BOCIAN, Wojciech , SITKOWSKI, Jerzy , BEDNAREK, Elzbieta , WIKTORSKA, Katarzyna , LUBELSKA, Katarzyna
IPC分类号： C07D491/22 , A61K31/4745 , A61P31/00 , A61P35/02
CPC分类号： C07D491/22
摘要： The subject of the present invention are water-soluble derivatives of camptothecin, their synthesis and use. These compounds exhibit preferable biological properties for use in anti-neoplasm therapy.
摘要翻译： 本发明的主题是喜树碱的水溶性衍生物，它们的合成和用途。 这些化合物在抗肿瘤治疗中表现出优选的生物学特性。
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6.发明公开NUCLEOTIDE ANALOGUE, METHOD OF SYNTHESIS OF NUCLEOTIDE ANALOGUE, USE OF NUCLEOTIDE ANALOGUE, ANTIVIRAL PRO-NUCLEOTIDE, PHARMACEUTICAL COMPOSITION 有权核苷酸类似物，PROCESS用于合成的核苷酸类似物，采用了核苷酸类似物，抗病PRONUCLEOTID，药物组合物
公开(公告)号：EP2630152A1
公开(公告)日：2013-08-28
申请号：EP11781885.6
申请日：2011-10-13
发明人： KRASZEWSKI, Adam , ROMANOWSKA, Joanna , SOBKOWSKI, Micha , SZYMANSKA-MICHALAK, Agnieszka , STAWINSKI, Jacek , BORYSKI, Jerzy , LIPNIACKI, Andrzej , PIASEK, Andrzej
CPC分类号： C07F9/65616 , C07F9/65586 , C07H19/10 , C07H19/20
摘要： The object of the invention are nucleotide analogues, antiviral pro-nucleotides, a use of nucleotide analogues and pharmaceutical composition, a phosphorylating agent for synthesis of nucleotide analogue, and a method of synthesis of nucleotide analogue. More precisely, the invention applies to the new group of nucleotide analogues and their use in partial or complete inhibition of human immunodeficiency virus (HIV).
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公开(公告)号：EP2872156B1
公开(公告)日：2017-08-09
申请号：EP13741984.2
申请日：2013-07-13
申请人： Instytut Biochemii I Biofizyki Polskiej Akademii Nauk , Instytut Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk , Narodowy Instytut Leków , Szkola Glówna Gospodarstwa Wiejskiego W Warszawie , Wojskowy Instytut Higieny I Epidemiologii
发明人： LOBOCKA, Malgorzata , GLOWACKA, Aleksandra , DABROWSKI, Kamil , HEJNOWICZ, Monika S. , GOZDEK, Agnieszka , WEBER-DABROWSKA, Beata , GÓRSKI, Andrzej , EMPEL, Joanna , HRYNIEWICZ, Waleria , KWIATEK, Magdalena , PARASION, Sylwia , GRYKO, Romuald
IPC分类号： A61K35/76
CPC分类号： G01N33/5085 , A61K35/76 , G01N2333/4353 , Y02A50/475 , Y02A50/481
摘要： The subject of the present invention is a novel use of a nematode in the evaluation of the therapeutic efficacy of bacteriophage preparations used in, or capable of being used in the treatment of infections caused by pathogenic bacteria in humans or animals.
摘要翻译： 本发明的主题是线虫在评价用于或能够用于治疗由人或动物中的致病细菌引起的感染的噬菌体制剂的治疗功效中的新用途。
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公开(公告)号：EP2912039B1
公开(公告)日：2017-07-12
申请号：EP13824167.4
申请日：2013-10-25
发明人： KOZERSKI, Lech , KAWECKI, Robert , NAUMCZUK, Beata , HYZ, Karolina , BOCIAN, Wojciech , SITKOWSKI, Jerzy , BEDNAREK, Elzbieta , WIKTORSKA, Katarzyna , LUBELSKA, Katarzyna
IPC分类号： C07D491/22 , A61K31/4745 , A61P31/00 , A61P35/02
CPC分类号： C07D491/22
摘要： The subject of the present invention are water-soluble derivatives of camptothecin, their synthesis and use. These compounds exhibit preferable biological properties for use in anti-neoplasm therapy.
摘要翻译： 本发明的主题是喜树碱的水溶性衍生物，它们的合成和用途。 这些化合物表现出用于抗肿瘤治疗的优选生物学性质。
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公开(公告)号：EP3971189A1
公开(公告)日：2022-03-23
申请号：EP21461575.9
申请日：2021-08-06
发明人： Kozerski, Lech , Naumczuk, Beata , Sitkowski, Jerzy , Bednarek, Elzbieta , Urbanowicz, Magdalena , Bocian, Wojciech , Wiktorska, Katarzyna
IPC分类号： C07D491/22 , A61P35/00
摘要： The subject of the present invention are water-soluble derivatives of camptothecin, their synthesis and use. These compounds exhibit preferable biological properties for use in anti-neoplasm therapy.
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公开(公告)号：EP3846790A1
公开(公告)日：2021-07-14
申请号：EP19857747.0
申请日：2019-09-03
发明人： WIKTORSKA, Katarzyna , MIELCZAREK, Lidia , KRUG, Pamela , MAZUR, Maciej , CHILMONCZYK, Zdzislaw , SUCHOCKI, Piotr , BARTEL, Marta , KUSMIERZ, Barbara
IPC分类号： A61K31/095 , A61K31/26 , A61P35/00
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