发明公开
- 专利标题： BICYCLIC INHIBITORS OF ALK
- 专利标题（中）： ALK的双环抑制剂
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申请号： EP12736704.3申请日： 2012-01-20
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公开(公告)号： EP2665725A1公开(公告)日： 2013-11-27
- 发明人: VASUDEVAN, Anil , PENNING, Thomas Dale , CHEN, Huanming , LIANG, Bo , WANG, Shaohui , ZHAO, Zhongqiang , CHAI, Dikun , YANG, Leifu , GAO, Yingxiang , PLIUSHCHEV, Marina
- 申请人： AbbVie Inc.
- 申请人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： 1 North Waukegan Road North Chicago, IL 60064 US
- 代理机构： Modiano, Micaela Nadia
- 优先权： PCT/CN2011/000110 20110121
- 国际公布： WO2012097683 20120726
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; C07D217/24 ; C07D239/88 ; A61K31/435 ; A61K31/495 ; A61P35/00
摘要：
The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, Formula (1) wherein R
1 , R
2 , R
3 , X, Y, Z, A, B, G
1 , m, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.
1 , R
2 , R
3 , X, Y, Z, A, B, G
1 , m, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.
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