公开(公告)号：EP2665725A1

公开(公告)日：2013-11-27

申请号：EP12736704.3

申请日：2012-01-20

申请人： AbbVie Inc.

发明人： VASUDEVAN, Anil ,  PENNING, Thomas Dale ,  CHEN, Huanming ,  LIANG, Bo ,  WANG, Shaohui ,  ZHAO, Zhongqiang ,  CHAI, Dikun ,  YANG, Leifu ,  GAO, Yingxiang ,  PLIUSHCHEV, Marina

IPC分类号： C07D471/04 ,  C07D217/24 ,  C07D239/88 ,  A61K31/435 ,  A61K31/495 ,  A61P35/00

CPC分类号： C07D471/04 ,  C07D401/12

摘要： The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, Formula (1) wherein R
1 , R
2 , R
3 , X, Y, Z, A, B, G
1 , m, and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.

摘要翻译： 本发明涉及式（1）化合物或其药学上可接受的盐，其中R 1，R 2，R 3，X，Y，Z，A，B，G 1，m和n在 说明。 本发明还涉及含有可用于抑制激酶如ALK的所述化合物的组合物和治疗疾病如癌症的方法。

公开(公告)号：EP2665724A1

公开(公告)日：2013-11-27

申请号：EP12736305.9

申请日：2012-01-20

申请人： AbbVie Inc.

发明人： VASUDEVAN, Anil ,  PENNING, Thomas Dale ,  CHEN, Huanming ,  LIANG, Bo ,  WANG, Shaohui ,  ZHAO, Zhongqiang ,  CHAI, Dikun ,  YANG, Leifu ,  GAO, Yingxiang ,  PLIUSHCHEV, Marina

IPC分类号： C07D471/04 ,  C07D239/88 ,  C07D237/32 ,  C07D243/14 ,  A61K31/435 ,  A61K31/495 ,  A61K31/551 ,  A61P35/00

CPC分类号： C07D471/04 ,  C07D401/12

摘要： The present invention relates to compounds of formula (1) or pharmaceutical acceptable salts, wherein R
1 , X, Y, Z, A, B, G
1 , and n are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as ALK and methods of treating diseases such as cancer.