发明公开
EP2714665A1 NEW 1-ARYLPIPERAZINIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF
审中-公开
NEW 1-芳哌嗪配体DESN 5-HT7受体及其用途
- 专利标题： NEW 1-ARYLPIPERAZINIC LIGANDS OF 5-HT7 RECEPTOR AND USE THEREOF
- 专利标题（中）： NEW 1-芳哌嗪配体DESN 5-HT7受体及其用途
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申请号： EP11721044.3申请日： 2011-05-24
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公开(公告)号： EP2714665A1公开(公告)日： 2014-04-09
- 发明人: LEOPOLDO, Marcello , LACIVITA, Enza , COLABUFO, Nicola, Antonio , DE GIORGIO, Paola , BERARDI, Francesco , PERRONE, Roberto
- 申请人： Università degli Studi di Bari "Aldo Moro"
- 申请人地址： Piazza Umberto I 70121 Bari (BA) IT
- 专利权人： Università degli Studi di Bari "Aldo Moro"
- 当前专利权人： Università degli Studi di Bari "Aldo Moro"
- 当前专利权人地址： Piazza Umberto I 70121 Bari (BA) IT
- 代理机构： Germinario, Claudio
- 国际公布： WO2012159662 20121129
- 主分类号： C07D239/26
- IPC分类号： C07D239/26 ; C07D241/12 ; C07D401/04 ; C07D295/084 ; A61K31/506 ; A61P25/06
摘要：
The invention relates to a new class of compounds able to inhibit with high affinity and selectivity the 5-HT7 receptor. The invention also relates to the utilization of such compounds as medicaments useful in the treatment and prevention of 5-HT7 receptor relating disorders of the central nervous system. The invention also relates to the isotopically labeled compounds for use in vivo diagnosis or imaging of a 5-HT7 condition.
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