发明公开
- 专利标题： SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS
- 专利标题（中）： 取代，如磺胺类药物抗凋亡BCL-抑制剂
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申请号： EP12726525.4申请日： 2012-05-23
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公开(公告)号： EP2714681A1公开(公告)日： 2014-04-09
- 发明人: BORZILLERI, Robert M. , CAI, Zhen-wei , TEBBEN, Andrew J. , PEREZ, Heidi L. , ZHANG, Liping , SCHROEDER, Gretchen M. , WEI, Donna D.
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： Post Office Box 4000 Route 206 and Province Line Road Princeton, NJ 05843-4000 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： Post Office Box 4000 Route 206 and Province Line Road Princeton, NJ 05843-4000 US
- 代理机构： Reitstötter - Kinzebach
- 优先权： US201161489865P 20110525
- 国际公布： WO2012162365 20121129
- 主分类号： C07D403/10
- IPC分类号： C07D403/10 ; C07D403/12 ; C07D403/14 ; C07D413/12 ; A61P35/00 ; A61K31/4166
摘要：
Disclosed are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein: W and Q and G are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bcl-2 family antiapoptotic proteins for the treatment of cancer; and pharmaceutical compositions comprising such compounds.
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