发明公开
EP2740724A1 COMPOUND FOR TREATING CARTILAGE DISORDERS 有权
VERBINDUNG ZUR BEHANDLUNG VON KNORPELERKRANKUNGEN

COMPOUND FOR TREATING CARTILAGE DISORDERS
摘要:
The present invention provides a compound of which active form is represented by a formula (A). and which can be injected into a joint cavity which is an affected part of disorders and can be accumulated in the joint cavity to exert the pharmacological effect thereof in a sustained manner, for the purpose of ameliorating cartilage disorders without developing any side effect. A compound according to the present invention, which is represented by a formula (I):

(wherein all of symbols are as defined in the description), is a compound that can achieve the above-mentioned purpose. This compound does not exhibit any side effect on the cardiovascular system even when the compound is administered in an effective amount for exhibiting a cartilage regeneration activity, and is therefore extremely useful as a safe and effective preventive and/or therapeutic agent for cartilage disorders. Since a suspension produced using this compound can be injected without requiring the incision of the affected part, it can reduce the burden on patients, and is extremely useful as a medicinal agent.
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