发明公开
EP2753352A1 ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C. DIFFICILE AND USES THEREOF
有权
一种分离的多肽毒素A和毒素B的艰难梭菌，及其用途
- 专利标题： ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C. DIFFICILE AND USES THEREOF
- 专利标题（中）： 一种分离的多肽毒素A和毒素B的艰难梭菌，及其用途
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申请号： EP11769799.5申请日： 2011-09-05
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公开(公告)号： EP2753352A1公开(公告)日： 2014-07-16
- 发明人: ELLINGSWORTH, Larry , FLYER, David , TIAN, Jing-Hui , FUHRMANN, Steven , KLUEPFEL-STAHL, Stefanie , GLENN, Gregory , WESTRITSCHNIG, Kerstin
- 申请人： Valneva Austria GmbH , Intercell USA, Inc.
- 申请人地址： Campus Vienna Biocenter 3 1030 Vienna AT
- 专利权人： Valneva Austria GmbH,Intercell USA, Inc.
- 当前专利权人： Valneva Austria GmbH,Intercell USA, Inc.
- 当前专利权人地址： Campus Vienna Biocenter 3 1030 Vienna AT
- 代理机构： Dempster, Robert Charles
- 国际公布： WO2012028741 20120308
- 主分类号： A61K39/08
- IPC分类号： A61K39/08 ; C07K14/33
摘要：
This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C. difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO: 2 and SEQ ID NO: 4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C. difficile toxin A and/or toxin B.
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