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1.发明授权ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C. DIFFICILE AND USES THEREOF 有权同义词多糖类毒素一种不良反应B AUS C. DIFFICILE UND VERWENDUNG DAVON
公开(公告)号：EP2753352B1
公开(公告)日：2017-01-25
申请号：EP11769799.5
申请日：2011-09-05
发明人： ELLINGSWORTH, Larry , FLYER, David , TIAN, Jing-Hui , FUHRMANN, Steven , KLUEPFEL-STAHL, Stefanie , GLENN, Gregory , WESTRITSCHNIG, Kerstin
CPC分类号： A61K39/08 , A61K2039/53 , A61K2039/55505 , A61K2039/55544 , A61K2039/575 , C07K14/33 , C07K16/1282 , C07K2317/76 , C07K2319/00 , C07K2319/40 , C07K2319/55
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2.发明公开ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C. DIFFICILE AND USES THEREOF 有权一种分离的多肽毒素A和毒素B的艰难梭菌，及其用途
公开(公告)号：EP2753352A1
公开(公告)日：2014-07-16
申请号：EP11769799.5
申请日：2011-09-05
发明人： ELLINGSWORTH, Larry , FLYER, David , TIAN, Jing-Hui , FUHRMANN, Steven , KLUEPFEL-STAHL, Stefanie , GLENN, Gregory , WESTRITSCHNIG, Kerstin
CPC分类号： A61K39/08 , A61K2039/53 , A61K2039/55505 , A61K2039/55544 , A61K2039/575 , C07K14/33 , C07K16/1282 , C07K2317/76 , C07K2319/00 , C07K2319/40 , C07K2319/55
摘要： This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C. difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO: 2 and SEQ ID NO: 4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C. difficile toxin A and/or toxin B.
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3.发明公开ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C.DIFFICILE AND USES THEREOF 审中-公开毒素A和毒素B蛋白的分离多肽及其用途
公开(公告)号：EP3167899A1
公开(公告)日：2017-05-17
申请号：EP16204515.7
申请日：2011-09-05
发明人： ELLINGSWORTH, Larry , FLYER, David , TIAN, Jing-Hui , FUHRMANN, Steven , KLUEPFEL-STAHL, Stefanie , GLENN, Gregory , WESTRITSCHNIG, Kerstin
CPC分类号： A61K39/08 , A61K2039/53 , A61K2039/55505 , A61K2039/55544 , A61K2039/575 , C07K14/33 , C07K16/1282 , C07K2317/76 , C07K2319/00 , C07K2319/40 , C07K2319/55
摘要： This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C.difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO:2 and SEQ ID NO:4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C.difficile toxin A and/or toxin B.
摘要翻译： 本发明提供了C-TAB.G5和C-TAB.G5.1分离的多肽，其包含如SEQ ID NO：2和SEQ ID NO：2的氨基酸序列中所示的C.difficile毒素A和毒素B的受体结合结构域 NO：4。 C-TAB.G5和C-TAB.G5.1分离的多肽可用于中和C.difficile毒素A和/或毒素B的毒性作用。
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4.发明公开
公开(公告)号：EP3895728A1
公开(公告)日：2021-10-20
申请号：EP21157982.6
申请日：2011-09-05
发明人： ELLINGSWORTH, Larry , FLYER, David , TIAN, Jing-Hui , FUHRMANN, Steven , KLUEPFEL-STAHL, Stefanie , GLENN, Gregory , WESTRITSCHNIG, Kerstin
摘要： This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C.difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO:2 and SEQ ID NO:4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C.difficile toxin A and/or toxin B.
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