发明公开
- 专利标题： HETEROCYCLIC-SUBSTITUED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
- 专利标题（中）： 杂环取代的苯并呋喃及其使用病毒病的治疗方法
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申请号： EP12829730申请日： 2012-08-16
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公开(公告)号： EP2753618A4公开(公告)日： 2015-03-18
- 发明人: MCCOMAS CASEY CAMERON , LIVERTON NIGEL J , HABERMANN JOERG , KOCH UWE , NARJES FRANK , LI PENG , PENG XUANJIA , SOLL RICHARD , WU HAO , PALANI ANANDAN , DAI XING , LIU HONG , HE SHUWEN , LAI ZHONG , DANG QUNG , ZORN NICHOLAS
- 申请人： MERCK SHARP & DOHME , MSD ITALIA SRL
- 专利权人： MERCK SHARP & DOHME,MSD ITALIA SRL
- 当前专利权人： MERCK SHARP & DOHME,MSD ITALIA SRL
- 优先权： CN2011079467 2011-09-08
- 主分类号： C07D413/14
- IPC分类号： C07D413/14 ; A61K31/343 ; A61P31/14 ; C07D405/14
摘要：
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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