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1.发明公开
公开(公告)号：EP2753618A4
公开(公告)日：2015-03-18
申请号：EP12829730
申请日：2012-08-16
发明人： MCCOMAS CASEY CAMERON , LIVERTON NIGEL J , HABERMANN JOERG , KOCH UWE , NARJES FRANK , LI PENG , PENG XUANJIA , SOLL RICHARD , WU HAO , PALANI ANANDAN , DAI XING , LIU HONG , HE SHUWEN , LAI ZHONG , DANG QUNG , ZORN NICHOLAS
IPC分类号： C07D413/14 , A61K31/343 , A61P31/14 , C07D405/14
CPC分类号： A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/444 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5365 , A61K31/5377 , A61K31/5383 , A61K31/695 , A61K45/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D498/04 , C07D513/04 , C07F7/10 , A61K31/424 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 本发明涉及式（I）也可用作丙型肝炎病毒（HCV）NS5B聚合酶的抑制剂，寻求化合物的合成，以及用于抑制HCV NS5B聚合酶活性，用于治疗或预防HCV感染的使用受试化合物的有用的化合物 和用于抑制HCV病毒复制和/或病毒的生产在基于细胞的系统。
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2.发明公开TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES 审中-公开四环和杂环衍生物AND METHOD FOR USE IN病毒病的治疗
公开(公告)号：EP2753325A4
公开(公告)日：2015-01-21
申请号：EP12830590
申请日：2012-08-20
发明人： MCCOMAS CASEY CAMERON , LIVERTON NIGEL J , HABERMANN JOERG , KOCH UWE , NARJES FRANK , LI PENG , PENG XUANJIA , SOLL RICHARD , WU HAO , PALANI ANANDAN , HE SHUWEN , DAI XING , LIU HONG , LAI ZHONG , LONDON CLARE , XIAO DONG , ZORN NICOLAS , NARGUND RAVI
IPC分类号： A61K31/343 , A61P31/14 , C07D307/82 , C07D405/10
CPC分类号： A61K31/553 , A61K31/407 , A61K31/437 , A61K31/519 , A61K31/5365 , A61K45/06 , C07D491/052 , C07D491/147 , C07D498/04 , C07D498/14 , C07D498/22 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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3.发明公开
公开(公告)号：EP2753611A4
公开(公告)日：2015-03-11
申请号：EP12829739
申请日：2012-08-16
发明人： MCCOMAS CASEY CAMERON , LIVERTON NIGEL J , HABERMANN JOERG , KOCH UWE , NARJES FRANK , LI PENG , PENG XUANJIA , SOLL RICHARD , WU HAO , PALANI ANANDAN , DAI XING , LIU HONG , HE SHUWEN , DANG QUNG
IPC分类号： C07D405/04 , A61K31/343 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/4375 , A61K31/4439 , A61K31/52 , A61K45/06 , A61P31/12 , A61P31/14 , C07D405/14 , C07D471/04 , C07D473/00 , C07D498/04
CPC分类号： C07D405/04 , A61K31/4045 , A61K31/416 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4439 , A61K31/4985 , A61K31/5025 , A61K31/52 , A61K45/06 , C07D405/14 , C07D471/04 , C07D473/00 , C07D487/04 , C07D498/04 , A61K2300/00
摘要： The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
摘要翻译： 本发明涉及式（I）也可用作丙型肝炎病毒（HCV）NS5B聚合酶的抑制剂，寻求化合物的合成，以及用于抑制HCV NS5B聚合酶活性，用于治疗或预防HCV感染的使用受试化合物的有用的化合物 和用于抑制HCV病毒复制和/或病毒的生产在基于细胞的系统。
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公开(公告)号：EP2542545A4
公开(公告)日：2013-12-25
申请号：EP11750145
申请日：2011-03-02
发明人： MCCOMAS CASEY CAMERON , LIVERTON NIGEL J , SOLL RICHARD , LI PENG , PENG XUANJIA , WU HAO , NARJES FRANK , HABERMANN JOERG , KOCH UWE , LIU SHILAN
IPC分类号： C07D307/84 , A61K31/343 , A61K45/06 , A61P31/14 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/10 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/10 , C07D471/04 , C07D473/00 , C07D487/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04
CPC分类号： C07D307/84 , A61K31/343 , A61K45/06 , C07D405/04 , C07D405/10 , C07D405/12 , C07D405/14 , C07D407/12 , C07D409/10 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/10 , C07D471/04 , C07D473/00 , C07D487/04 , C07D491/04 , C07D495/04 , C07D498/04 , C07D513/04 , A61K2300/00
摘要： Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
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