发明公开
EP2805947A1 PIPERAZINYL PYRIMIDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF
有权
哌嗪基嘧啶衍生物，其制备方法和用途
- 专利标题： PIPERAZINYL PYRIMIDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF
- 专利标题（中）： 哌嗪基嘧啶衍生物，其制备方法和用途
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申请号： EP13738361.8申请日： 2013-01-15
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公开(公告)号： EP2805947A1公开(公告)日： 2014-11-26
- 发明人: LI, Song , WANG, Ying , XIAO, Junhai , MA, Dalong , GONG, Hongwei , QI, Hui , WANG, Lili , LING, Xiaomei , ZHENG, Zhibing , ZHANG, Yang , ZHONG, Wu , LI, Meina , XIE, Yunde , XU, Enquan , LI, Xingzhou , MA, Jing , ZHAO, Guoming , ZHOU, Xinbo , WANG, Xiaokui , LIU, Hongying
- 申请人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China , Peking University
- 申请人地址： No. 27, Taiping Road Haidian District Beijing 100-850 CN
- 专利权人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China,Peking University
- 当前专利权人： Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China,Peking University
- 当前专利权人地址： No. 27, Taiping Road Haidian District Beijing 100-850 CN
- 代理机构： Böhm, Brigitte
- 优先权： CN201210011263 20120116
- 国际公布： WO2013107333 20130725
- 主分类号： C07D403/14
- IPC分类号： C07D403/14 ; A61K31/506 ; A61K31/519 ; A61P11/06 ; A61P17/00
摘要：
Provided are piperazinyl pyrimidine derivatives of formula I having CCR 4 antagonism, and the preparation method, pharmaceutical composition and use thereof in the preparation of a medicament. The medicament is useful for the treatment and prevention of CCR 4 -related diseases.
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