发明公开
EP2816037A2 New 1-arylpiperazinic ligands of 5-HT7 receptor and use thereof
审中-公开
Neue 1-Arylpiperazin-Liganden vom 5-HT7-Rezeptor und Verwendung davon
- 专利标题： New 1-arylpiperazinic ligands of 5-HT7 receptor and use thereof
- 专利标题（中）： Neue 1-Arylpiperazin-Liganden vom 5-HT7-Rezeptor und Verwendung davon
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申请号： EP14179594.8申请日： 2011-05-24
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公开(公告)号： EP2816037A2公开(公告)日： 2014-12-24
- 发明人: Leopoldo, Marcello , Lacivita, Enza , Colabufo, Nicola Antonio , De Giorgio, Paola , Berardi, Francesco , Perrone, Roberto
- 申请人： Università degli Studi di Bari "Aldo Moro"
- 申请人地址： Piazza Umberto I, 1 70121 Bari (BA) IT
- 专利权人： Università degli Studi di Bari "Aldo Moro"
- 当前专利权人： Università degli Studi di Bari "Aldo Moro"
- 当前专利权人地址： Piazza Umberto I, 1 70121 Bari (BA) IT
- 代理机构： Germinario, Claudio
- 主分类号： C07D239/26
- IPC分类号： C07D239/26 ; C07D241/12 ; C07D401/04 ; C07D295/084 ; A61K31/506 ; A61P25/06
摘要：
The invention relates to a new class of compounds able to inhibit with high affinity and selectivity the 5-HT7 receptor. The invention also relates to the utilization of such compounds as medicaments useful in the treatment and prevention of 5-HT7 receptor relating disorders of the central nervous system. The invention also relates to the isotopically labeled compounds for use in vivo diagnosis or imaging of a 5-HT7 condition.
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