发明公开
- 专利标题： ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES
- 专利标题（中）： 抗菌剂：芳基MYXRYRONIN衍生物
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申请号： EP13733201.1申请日： 2013-06-19
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公开(公告)号： EP2861570A1公开(公告)日： 2015-04-22
- 发明人: EBRIGHT, Richard H. , EBRIGHT, Yon W. , SHEN, Juan , BACCI, James , HIEBEL, Anne-Cecile , SOLVIBILE, William , SELF, Christopher , OLSON, Gary
- 申请人： Rutgers, The State University of New Jersey , Provid Pharmaceuticals Inc. , Ebright, Richard H. , Ebright, Yon W. , Shen, Juan , Bacci, James , Hiebel, Anne-Cecile , Solvibile, William , Self, Christopher , Olson, Gary
- 申请人地址： Old Queens Building Somerset and George Streets New Brunswick, NJ 08903 US
- 专利权人： Rutgers, The State University of New Jersey,Provid Pharmaceuticals Inc.,Ebright, Richard H.,Ebright, Yon W.,Shen, Juan,Bacci, James,Hiebel, Anne-Cecile,Solvibile, William,Self, Christopher,Olson, Gary
- 当前专利权人： Rutgers, The State University of New Jersey,Provid Pharmaceuticals Inc.,Ebright, Richard H.,Ebright, Yon W.,Shen, Juan,Bacci, James,Hiebel, Anne-Cecile,Solvibile, William,Self, Christopher,Olson, Gary
- 当前专利权人地址： Old Queens Building Somerset and George Streets New Brunswick, NJ 08903 US
- 代理机构： Müller-Boré & Partner Patentanwälte PartG mbB
- 优先权： US201261661670P 20120619
- 国际公布： WO2013192352 20131227
- 主分类号： C07D309/38
- IPC分类号： C07D309/38 ; C07D405/06 ; C07D407/06 ; C07D407/12 ; C07D409/06 ; C07D417/06 ; A61P31/00 ; A61K31/366 ; A61K31/381 ; A61K31/4433 ; A61K31/404 ; A61K31/4178 ; A61K31/427
摘要：
The invention provides compounds of formula la, lb and Ic: [Formula Ia, Ib, and Ic] and salts thereof, wherein variables are as described in the specification, as well as compositions comprising a compound of formula Ia-Ic, methods of making such compounds, and methods of using such compounds, e.g., as inhibitors of bacterial RNA polymerase and as antibacterial agents.
公开/授权文献
- EP2861570B1 ANTIBACTERIAL AGENTS: ARYL MYXOPYRONIN DERIVATIVES 公开/授权日：2018-07-18
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