发明公开
EP2886556A2 NOVEL MONOCLONAL ANTIBODY WHICH IS SPECIFICALLY BOUND TO TM4SF5 PROTEIN AND USE THEREOF
有权
具有特异性结合蛋白及其用途新型单克隆抗体TM4SF5-
- 专利标题： NOVEL MONOCLONAL ANTIBODY WHICH IS SPECIFICALLY BOUND TO TM4SF5 PROTEIN AND USE THEREOF
- 专利标题（中）： 具有特异性结合蛋白及其用途新型单克隆抗体TM4SF5-
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申请号： EP13824875.2申请日： 2013-08-05
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公开(公告)号： EP2886556A2公开(公告)日： 2015-06-24
- 发明人: KIM, Se Mi , KIM, Sang Jick , MIN, Hye Jin , SONG, Jin Myeong , LEE, Jung Weon , KIM, Hye Jin , AHN, Hye Mi , CHOI, In Pyo , RYU, Ji Hye
- 申请人： Korea Research Institute of Bioscience and Biotechology , SNU R&DB Foundation
- 申请人地址： 125 Gwahak-ro Yuseong-gu Daejeon 305-806 KR
- 专利权人： Korea Research Institute of Bioscience and Biotechology,SNU R&DB Foundation
- 当前专利权人： Korea Research Institute of Bioscience and Biotechology,SNU R&DB Foundation
- 当前专利权人地址： 125 Gwahak-ro Yuseong-gu Daejeon 305-806 KR
- 代理机构： Sonn & Partner Patentanwälte
- 优先权： KR20120085436 20120803; KR20120085437 20120803
- 国际公布： WO2014021693 20140206
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; A61P35/00 ; G01N33/574
摘要：
The present invention relates to a novel monoclonal antibody which is specifically bound to a transmembrane 4 L six family member 5 (TM4SF5) protein. More particularly, the present invention relates to a monoclonal antibody which is specifically bound to a human TM4SF5 protein, to polynucleotides coding for the monoclonal antibody, to an expression vector comprising the nucleotides, to a transformant with the vector introduced thereto, to a method for preparing the monoclonal antibody, to a composition comprising the monoclonal antibody, to a method for treating cancer using the monoclonal antibody, to a method for inhibiting liver metastasis of cancer, to a method for diagnosing cancer using the monoclonal antibody and to a cancer diagnosis kit comprising the monoclonal antibody.
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