发明公开
- 专利标题： ANTIBODY EVOLUTION IMMUNOGENS
- 专利标题（中）： 抗体演化免疫原
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申请号： EP13837551.4申请日： 2013-09-12
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公开(公告)号： EP2895500A1公开(公告)日： 2015-07-22
- 发明人: HAYNES, Barton, F. , LIAO, Hua-Xin , LYNCH, Rebecca, M. , ZHOU, Tongqing , GAO, Feng , BOYD, Scott , SHAW, George, M. , HAHN, Beatrice, H. , KEPLER, Thomas, B. , KORBER, Bette, T. , KWONG, Peter , MASCOLA, John
- 申请人： Duke University , Los Alamos National Security LLC , The Trustees Of The University Of Pennsylvania , Trustees of Boston University , The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services , The Board of Trustees of the Leland Stanford Junior University
- 申请人地址： 2812 Erwin Road Durham, NC 27705 US
- 专利权人： Duke University,Los Alamos National Security LLC,The Trustees Of The University Of Pennsylvania,Trustees of Boston University,The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services,The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人： Duke University,Los Alamos National Security LLC,The Trustees Of The University Of Pennsylvania,Trustees of Boston University,The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services,The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人地址： 2812 Erwin Road Durham, NC 27705 US
- 代理机构： Atkinson, Peter Birch
- 优先权： US201261700252P 20120912; US201261708466P 20121001; US201361764421P 20130213
- 国际公布： WO2014042669 20140320
- 主分类号： C07K14/155
- IPC分类号： C07K14/155 ; A61K39/12 ; A61P31/18
摘要：
The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).
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