公开(公告)号：EP2895500A1

公开(公告)日：2015-07-22

申请号：EP13837551.4

申请日：2013-09-12

申请人： Duke University ,  Los Alamos National Security LLC ,  The Trustees Of The University Of Pennsylvania ,  Trustees of Boston University ,  The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services ,  The Board of Trustees of the Leland Stanford Junior University

发明人： HAYNES, Barton, F. ,  LIAO, Hua-Xin ,  LYNCH, Rebecca, M. ,  ZHOU, Tongqing ,  GAO, Feng ,  BOYD, Scott ,  SHAW, George, M. ,  HAHN, Beatrice, H. ,  KEPLER, Thomas, B. ,  KORBER, Bette, T. ,  KWONG, Peter ,  MASCOLA, John

IPC分类号： C07K14/155 ,  A61K39/12 ,  A61P31/18

CPC分类号： A61K39/21 ,  A61K39/12 ,  A61K2039/57 ,  C07K14/005 ,  C12N7/00 ,  C12N2740/15022 ,  C12N2740/16022 ,  C12N2740/16122 ,  C12N2740/16134

摘要： The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).

摘要翻译： 本发明一般涉及HIV-1，特别涉及广泛中和HIV-1抗体和HIV-1免疫原，以及涉及使用此类免疫原以诱导产生广泛中和HIV-1抗体的方法 主题（例如，人）。