- 专利标题： DOUBLE-STRANDED OLIGONUCLEOTIDE MOLECULES TO P53 AND METHODS OF USE THEREOF
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申请号： EP13776599.6申请日： 2013-09-12
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公开(公告)号： EP2895608B1公开(公告)日： 2018-12-05
- 发明人: FEINSTEIN, Elena , AVKIN-NACHUM, Sharon , KALINSKI, Hagar , METT, Igor
- 申请人： Quark Pharmaceuticals, Inc.
- 申请人地址： 6501 Dumbarton Circle Fremont, California 94555 US
- 专利权人： Quark Pharmaceuticals, Inc.
- 当前专利权人： Quark Pharmaceuticals, Inc.
- 当前专利权人地址： 6501 Dumbarton Circle Fremont, California 94555 US
- 代理机构： Zimmermann & Partner Patentanwälte mbB
- 优先权： US201261699885P 20120912
- 国际公布： WO2014043292 20140320
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/713
摘要：
The present application relates to nucleic acid compounds, compositions comprising same and methods of use thereof for treatment of various diseases, disorders and conditions. The compounds are preferably chemically synthesized and modified double-stranded nucleic acid molecules which down regulate expression of a p53 gene.
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