Invention Grant
- Patent Title: 2,2-DIFLUORODIOXOLO A2A RECEPTOR ANTAGONISTS
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Application No.: EP14840648.1Application Date: 2014-08-25
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Publication No.: EP3038466B1Publication Date: 2018-05-23
- Inventor: ALI, Amjad , GALLO, Gioconda, V. , HENDERSON, Timothy, J. , KUANG, Rongze , LIM, Yeon-Hee , LO, Michael Man-Chu , METZGER, Edward , RUIZ, Manuel de Lera , STAMFORD, Andrew , TEMPEST, Paul , WHITEHEAD, Brent , WU, Heping
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- Agency: Jaap, David Robert
- Priority: PCT/CN2013/082560 20130829
- International Announcement: WO2015031221 20150305
- Main IPC: C07D519/00
- IPC: C07D519/00 ; C07D491/147 ; A61K31/519 ; A61P25/00 ; A61P25/16 ; A61P25/28
Abstract:
The present invention is directed to 2,2-difluorodioxolo compounds that are antagonists of A2A receptor. The present invention is also directed to uses of the 2,2-difluorodioxolo compounds described herein in the potential treatment or prevention of neurological disorders and diseases in which A2A receptor are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds and to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which A2A receptors are involved.
Public/Granted literature
- EP3038466A1 2,2-DIFLUORODIOXOLO A2A RECEPTOR ANTAGONISTS Public/Granted day:2016-07-06
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