发明公开
EP3058941A1 NOVEL STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL INHIBITORS
审中-公开
新型STAT3途径抑制剂和癌症干细胞抑制剂
- 专利标题: NOVEL STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL INHIBITORS
- 专利标题(中): 新型STAT3途径抑制剂和癌症干细胞抑制剂
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申请号: EP16156290.5申请日: 2008-09-10
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公开(公告)号: EP3058941A1公开(公告)日: 2016-08-24
- 发明人: JIANG, Zhiwei , LI, Chiang, Jia , LI, Wei , LEGGETT, David
- 申请人: Boston Biomedical, Inc.
- 申请人地址: 640 Memorial Drive Cambridge, MA 02139 US
- 专利权人: Boston Biomedical, Inc.
- 当前专利权人: Boston Biomedical, Inc.
- 当前专利权人地址: 640 Memorial Drive Cambridge, MA 02139 US
- 代理机构: Finnie, Isobel Lara
- 优先权: US971144P 20070910; US13372 20071213
- 主分类号: A61K31/505
- IPC分类号: A61K31/505 ; A61K31/55 ; A61K38/17
摘要:
The present invention relates to a novel naphtho class of compounds as Stat3 pathway inhibitors and as cancer stem cell inhibitors; to methods of using such compounds to treat cancer; to methods of using such compounds to treat disorders in a mammal related to aberrant Stat3 pathway activity; to pharmaceutical compositions containing such compounds.
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