发明公开
- 专利标题： PURINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY
- 专利标题（中）： 嘌呤衍生物作为TNF-活性的调节剂
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申请号： EP14809008.7申请日： 2014-12-08
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公开(公告)号： EP3080126A1公开(公告)日： 2016-10-19
- 发明人: JACKSON, Victoria Elizabeth , KROEPLIEN, Boris , LOWE, Martin Alexander , PORTER, John Robert
- 申请人： UCB Biopharma SPRL
- 申请人地址： Allée de la Recherche 60 1070 Brussels BE
- 专利权人： UCB Biopharma SPRL
- 当前专利权人： UCB Biopharma SPRL
- 当前专利权人地址： Allée de la Recherche 60 1070 Brussels BE
- 代理机构： Duckworth, Timothy John
- 优先权： GB201321737 20131209
- 国际公布： WO2015086505 20150618
- 主分类号： C07D473/32
- IPC分类号： C07D473/32 ; A61K31/52 ; A61P29/00
摘要：
A series of substituted purine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
公开/授权文献
- EP3080126B1 PURINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY 公开/授权日：2019-08-28
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