Invention Publication
EP3087060A1 PYRIMIDONE CARBOXAMIDE COMPOUNDS AS PDE2 INHIBITORS
审中-公开
吡咯烷 - 卡博胺 - 维生素ALS PDE2-INHIBITOREN
- Patent Title: PYRIMIDONE CARBOXAMIDE COMPOUNDS AS PDE2 INHIBITORS
- Patent Title (中): 吡咯烷 - 卡博胺 - 维生素ALS PDE2-INHIBITOREN
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Application No.: EP14873215.9Application Date: 2014-12-17
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Publication No.: EP3087060A1Publication Date: 2016-11-02
- Inventor: SHEN, Dong-Ming , EGBERTSON, Melissa , BERGER, Richard , QIAN, XiaoXia , QIAN, Yimin , HARPER, Bart , YANG, Meng , GUO, Zack Zhi Qiang , RADA, Vanessa L. , WANG, Deping , CERNAK, Timothy A. , SINZ, Christopher J. , WANG, Ming , WILSON, Jonathan E. , XU, Shimin
- Applicant: Merck Sharp & Dohme Corp. , MSD R & D (China) Co. Ltd.
- Applicant Address: 126 East Lincoln Avenue Rahway, NJ 07065 US
- Assignee: Merck Sharp & Dohme Corp.,MSD R & D (China) Co. Ltd.
- Current Assignee: Merck Sharp & Dohme Corp.,MSD R & D (China) Co. Ltd.
- Current Assignee Address: 126 East Lincoln Avenue Rahway, NJ 07065 US
- Agency: Buchan, Gavin MacNicol
- Priority: US201361920270P 20131223
- International Announcement: WO2015096651 20150702
- Main IPC: C07D239/36
- IPC: C07D239/36 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D405/14 ; A61K31/513 ; A61P25/18 ; A61P25/22 ; A61P25/28
Abstract:
Disclosed are pyrimidine carboxamide compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2), pharmaceutical compositions and uses thereof.
Public/Granted literature
- EP3087060B1 PYRIMIDONE CARBOXAMIDE COMPOUNDS AS PDE2 INHIBITORS Public/Granted day:2020-05-13
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