发明公开
EP3102192A2 USE OF CASEIN KINASE I INHIBITORS FOR DEPLETING STEM CELLS
审中-公开
VERWENDUNG VON CASEIN-KINASE-I-HEMMERN ZUR ABREICHERUNG VON STAMMZELLEN
- 专利标题： USE OF CASEIN KINASE I INHIBITORS FOR DEPLETING STEM CELLS
- 专利标题（中）： VERWENDUNG VON CASEIN-KINASE-I-HEMMERN ZUR ABREICHERUNG VON STAMMZELLEN
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申请号： EP15706542.6申请日： 2015-02-03
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公开(公告)号： EP3102192A2公开(公告)日： 2016-12-14
- 发明人: BEN-NERIAH, Yinon , MINZEL, Waleed , BRACHYA, Guy
- 申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- 申请人地址： Hi Tech Park, The Edmond J. Safra Campus The Hebrew University of Jerusalem Givat Ram P.O. Box 39135 9139002 Jerusalem IL
- 专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- 当前专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
- 当前专利权人地址： Hi Tech Park, The Edmond J. Safra Campus The Hebrew University of Jerusalem Givat Ram P.O. Box 39135 9139002 Jerusalem IL
- 代理机构： Handley, Matthew Edward
- 优先权： US201461934954P 20140203
- 国际公布： WO2015114638 20150806
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/506 ; A61K35/12 ; C12Q1/00 ; A61P35/00 ; A61P35/02
摘要：
A method of treating cancer in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of a Casein kinase I alpha (CKIalpha) inhibitor, wherein the cancer is not associated with an Adenomatous polyposis coli (APC) mutation. Additional uses of CKI inhibitors are also disclosed.
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