专利检索 ap:("Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.") AND inv:"BEN-NERIAH, Yinon" 第 1 页

1.

发明公开
USE OF CASEIN KINASE I INHIBITORS FOR DEPLETING STEM CELLS 审中-公开
标题翻译： VERWENDUNG VON CASEIN-KINASE-I-HEMMERN ZUR ABREICHERUNG VON STAMMZELLEN

公开(公告)号：EP3102192A2

公开(公告)日：2016-12-14

申请号：EP15706542.6

申请日：2015-02-03

申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

发明人： BEN-NERIAH, Yinon , MINZEL, Waleed , BRACHYA, Guy

IPC分类号： A61K31/00 , A61K31/506 , A61K35/12 , C12Q1/00 , A61P35/00 , A61P35/02

CPC分类号： A61K31/506 , A61K31/00 , A61K35/12 , A61K35/14 , A61K35/28 , C12N15/1137 , C12N2310/14 , G01N33/502 , G01N33/5073

摘要： A method of treating cancer in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of a Casein kinase I alpha (CKIalpha) inhibitor, wherein the cancer is not associated with an Adenomatous polyposis coli (APC) mutation. Additional uses of CKI inhibitors are also disclosed.

摘要翻译： 公开了一种治疗受试者的癌症的方法。该方法包括向受试者施用治疗有效量的酪蛋白激酶Iα（CKIα）抑制剂，其中所述癌症与腺瘤性息肉病大肠杆菌（APC）突变不相关。还公开了CKI抑制剂的其它用途。

2.

发明公开
N1 -(4-(5-(CYCLOPROPYLMETHYL)-1 -METHYL-1 H-PYRAZOL-4-YL)PYRIDIN-2-YL)CYCLOHEXANE-1,4-DIAMINE DERIVATIVES AND RELATED COMPOUNDS AS CK1 AND/OR IRAKI INHIBITORS FOR TREATING CANCER 审中-公开

公开(公告)号：EP3577108A1

公开(公告)日：2019-12-11

申请号：EP18705024.0

申请日：2018-01-30

申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd

发明人： LI, Dansu , SNIR-ALKALAY, Irit , VACCA, Joseph , BEN-NERIAH, Yinon , VENKATAC-IALAM, Avanthika

IPC分类号： C07D401/04 , C07D403/04 , C07D417/04 , A61K31/4439 , A61K31/506 , A61K31/4155 , A61K31/427 , A61P35/00