发明公开
EP3151921A2 ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR NECROSIS FACTOR RECEPTOR (GITR) AND USES THEREOF
审中-公开
抗生素GEGEN GLUCOCORTICOIDINDUZIERTEN TUMORNEKROSEFAKTORREZEPTOR(GITR)UND VERWENDUNGEN DAVON
- 专利标题: ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR NECROSIS FACTOR RECEPTOR (GITR) AND USES THEREOF
- 专利标题(中): 抗生素GEGEN GLUCOCORTICOIDINDUZIERTEN TUMORNEKROSEFAKTORREZEPTOR(GITR)UND VERWENDUNGEN DAVON
-
申请号: EP15742414.4申请日: 2015-06-03
-
公开(公告)号: EP3151921A2公开(公告)日: 2017-04-12
- 发明人: WANG, Changyu , LONBERG, Nils , KORMAN, Alan J. , SELBY, Mark J. , SRINIVASAN, Mohan , HENNING, Karla , HAN, Michelle, Minhua , CHEN, Guodong , HUANG, Richard , CHAKRABORTY, Indrani , HUANG, Haichun , WONG, Susan , LI, Huiming
- 申请人: Bristol-Myers Squibb Company
- 申请人地址: Route 206 and Province Line Road Princeton, NJ 08543 US
- 专利权人: Bristol-Myers Squibb Company
- 当前专利权人: Bristol-Myers Squibb Company
- 当前专利权人地址: Route 206 and Province Line Road Princeton, NJ 08543 US
- 代理机构: Reitstötter Kinzebach
- 优先权: US201462008945P 20140606; US201462082980P 20141121
- 国际公布: WO2015187835 20151210
- 主分类号: A61P35/00
- IPC分类号: A61P35/00 ; A61K39/00 ; C07K16/28
摘要:
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
公开/授权文献
信息查询
IPC分类:
A | 人类生活必需 |
A61 | 医学或兽医学;卫生学 |
A61P | 化合物或药物制剂的特定治疗活性 |
A61P35/00 | 抗肿瘤药 |