- 专利标题： VECTOR COMPRISING GENE FRAGMENT FOR ENHANCEMENT OF RECOMBINANT PROTEIN EXPRESSION AND USE THEREOF
-
申请号： EP15810394.5申请日： 2015-06-16
-
公开(公告)号： EP3159411B1公开(公告)日： 2018-07-25
- 发明人: LEE, Eun Gyo , LEE, Hong-Weon , KANG, Shin Young , KIM, Yeon-Gu , JUNG, Joon Ki , AHN, Jungoh , KANG, Seung Hee , KIM, Chun Sug , LEE, Hyeok Won , LEE, Jin Gyeom
- 申请人： Korea Research Institute of Bioscience and Biotechnology
- 申请人地址： 125, Gwahak-ro Eoeun-dong Yuseong-gu Daejeon 305-806 KR
- 专利权人： Korea Research Institute of Bioscience and Biotechnology
- 当前专利权人： Korea Research Institute of Bioscience and Biotechnology
- 当前专利权人地址： 125, Gwahak-ro Eoeun-dong Yuseong-gu Daejeon 305-806 KR
- 代理机构： Cabinet Laurent & Charras
- 优先权： KR20140073443 20140617
- 国际公布： WO2015194834 20151223
- 主分类号： C12N15/63
- IPC分类号： C12N15/63 ; C12N15/85 ; C12N5/10 ; C12Q1/68 ; C12P21/02
摘要：
The present invention relates to a new gene fragment derived from Chinese hamster ovary (CHO) cell for enhancement of recombinant protein expression in animal cells and a use thereof. It has been found that using the vector comprising a gene fragment of the present invention enhances the expression of a target protein in animal cells. Accordingly, the vector comprising a gene fragment of the present invention could be usefully used in the production of biopharmaceuticals such as therapeutic antibodies, etc.
公开/授权文献
信息查询
IPC分类:
