-
公开(公告)号：EP3378940B1
公开(公告)日：2020-06-03
申请号：EP16860244.9
申请日：2016-10-27
发明人： AHN, Jung Oh , LEE, Hong Weon , JANG, Min Jeong , KIM, Chun Sug , PARK, Gyu Yeon
-
2.发明公开VECTOR COMPRISING GENE FRAGMENT FOR ENHANCEMENT OF RECOMBINANT PROTEIN EXPRESSION AND USE THEREOF 有权包含基因片段的增强重组蛋白表达的载体及其应用
公开(公告)号：EP3159411A1
公开(公告)日：2017-04-26
申请号：EP15810394.5
申请日：2015-06-16
发明人： LEE, Eun Gyo , LEE, Hong-Weon , KANG, Shin Young , KIM, Yeon-Gu , JUNG, Joon Ki , AHN, Jungoh , KANG, Seung Hee , KIM, Chun Sug , LEE, Hyeok Won , LEE, Jin Gyeom
CPC分类号： C12N15/85 , C07K14/43595 , C07K16/00 , C07K2317/14 , C12N15/63 , C12N2840/203 , C12N2840/60 , C12N2840/85 , C12Q1/68 , C12Q1/6876 , C12Q1/6897
摘要： The present invention relates to a new gene fragment derived from Chinese hamster ovary (CHO) cell for enhancement of recombinant protein expression in animal cells and a use thereof. It has been found that using the vector comprising a gene fragment of the present invention enhances the expression of a target protein in animal cells. Accordingly, the vector comprising a gene fragment of the present invention could be usefully used in the production of biopharmaceuticals such as therapeutic antibodies, etc.
摘要翻译： 本发明涉及用于增强动物细胞中重组蛋白质表达的源自中国仓鼠卵巢（CHO）细胞的新基因片段及其用途。 已经发现使用包含本发明基因片段的载体可增强动物细胞中靶蛋白的表达。 因此，包含本发明的基因片段的载体可以有效地用于生物药物例如治疗性抗体等的生产中
-
公开(公告)号：EP3378940A1
公开(公告)日：2018-09-26
申请号：EP16860244.9
申请日：2016-10-27
发明人： AHN, Jung Oh , LEE, Hong Weon , JANG, Min Jeong , KIM, Chun Sug , PARK, Gyu Yeon
摘要： The present invention relates to a method for producing medium chain diol and, more particularly to recombinant microorganisms in which fatty alcohol dehydrogenase and/or fatty alcohol oxidase genes on a ω-oxidative metabolism pathway are deleted, the fatty aldehyde dehydrogenase genes are optionally deleted, and β-oxidative metabolism pathway-related genes are deleted, and to a method for producing medium chain diol from fatty acid-derived alcohol or alkane by culturing the recombinant microorganisms. The recombinant microorganisms of the present invention can produce a high yield of medium chain diol by preventing further oxidation and β-oxidative metabolism of fatty alcohols.
-
4.发明授权
公开(公告)号：EP3159411B1
公开(公告)日：2018-07-25
申请号：EP15810394.5
申请日：2015-06-16
发明人： LEE, Eun Gyo , LEE, Hong-Weon , KANG, Shin Young , KIM, Yeon-Gu , JUNG, Joon Ki , AHN, Jungoh , KANG, Seung Hee , KIM, Chun Sug , LEE, Hyeok Won , LEE, Jin Gyeom
CPC分类号： C12N15/85 , C07K14/43595 , C07K16/00 , C07K2317/14 , C12N15/63 , C12N2840/203 , C12N2840/60 , C12N2840/85 , C12Q1/68 , C12Q1/6876 , C12Q1/6897
摘要： The present invention relates to a new gene fragment derived from Chinese hamster ovary (CHO) cell for enhancement of recombinant protein expression in animal cells and a use thereof. It has been found that using the vector comprising a gene fragment of the present invention enhances the expression of a target protein in animal cells. Accordingly, the vector comprising a gene fragment of the present invention could be usefully used in the production of biopharmaceuticals such as therapeutic antibodies, etc.
-
-
-
搜索结果
4 条记录 (耗时 0.013 秒)
