发明公开
EP3183268A1 ANTI-CD123 CHIMERIC ANTIGEN RECEPTOR (CAR) FOR USE IN CANCER TREATMENT
审中-公开
抗癌CD123嵌合抗原受体（CAR）用于癌症治疗
- 专利标题： ANTI-CD123 CHIMERIC ANTIGEN RECEPTOR (CAR) FOR USE IN CANCER TREATMENT
- 专利标题（中）： 抗癌CD123嵌合抗原受体（CAR）用于癌症治疗
-
申请号： EP15756525.0申请日： 2015-08-19
-
公开(公告)号： EP3183268A1公开(公告)日： 2017-06-28
- 发明人: KENDERIAN, Saad , BROGDON, Jennifer , GILL, Saar , GLASS, David , LOEW, Andreas , MANNICK, Joan , MILONE, Michael , MURPHY, Leon , PORTER, David L. , RUELLA, Marco , WANG, Yongqiang , WU, Qilong , ZHANG, Jiquan
- 申请人： Novartis AG , The Trustees of The University of Pennsylvania
- 申请人地址： Lichtstrasse 35 4056 Basel CH
- 专利权人： Novartis AG,The Trustees of The University of Pennsylvania
- 当前专利权人： Novartis AG,The Trustees of The University of Pennsylvania
- 当前专利权人地址： Lichtstrasse 35 4056 Basel CH
- 代理机构： Wilding, James Roger
- 优先权： PCT/CN2014/084696 20140819; PCT/CN2014/090508 20141106
- 国际公布： WO2016028896 20160225
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395
摘要：
The invention provides compositions and methods for treating diseases associated with expression of CD123. The invention also relates to chimeric antigen receptor (CAR) specific to CD123, vectors encoding the same, and recombinant cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified cell expressing a CAR that comprises a CD123 binding domain.
公开/授权文献
信息查询
